Evidence map›Paper›PMID 39335006›Full record

ArticleAntibiotics (Basel, Switzerland)2024

An Institutional Febrile Neutropenia Protocol Improved the Antibacterial Treatment and Encouraged the Development of a Computerized Clinical Decision Support System.

Zahit Taş, Gökhan Metan, Gülçin Telli Dizman, Eren Yavuz, Ömer Dizdar, Yahya Büyükaşık, Ömrüm Uzun, Murat Akova

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zahit TaşDepartment of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.ORCID 0000-0003-1292-5951
Gökhan MetanDepartment of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.ORCID 0000-0002-2676-4557
Gülçin Telli DizmanDepartment of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.ORCID 0000-0001-8195-3345
Eren YavuzHemosoft Software Development Department, Ankara 06800, Turkey.
Ömer DizdarDepartment of Medical Oncology, Hacettepe University Faculty of Medicine, Ankara 06230, Turkey.ORCID 0000-0003-0911-9078
Yahya BüyükaşıkDepartment of Hematology, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.
Ömrüm UzunDepartment of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.ORCID 0000-0003-4721-0139
Murat AkovaDepartment of Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.ORCID 0000-0002-6904-9473

Funding

Abdi İbrahim Pharmaceuticals
6 · The paper itself

Abstract

We investigated the influence of a local guideline on the quality of febrile neutropenia (FN) management and the applicability of a computerized decision support system (CDSS) using real-life data. The study included 227 FN patients between April 2016 and January 2019. The primary outcome measure was the achievement of a 20% increase in the rate of appropriate empirical treatment of FN in bacteremic patients. The compatibility of the CDSS (the development of which was completed in November 2021) with local protocols was tested using standard patient scenarios and empirical antibiotic recommendations for bacteremic FN patients. In total, 91 patients were evaluated before (P1: between April 2016 and May 2017) and 136 after (P2: between May 2017 and January 2019) the guideline's release (May 2017). The demographic characteristics were similar. Appropriate empirical antibacterial treatment was achieved in 58.3% of P1 and 88.1% of P2 patients (

Indexed as

cancercomputerized clinical decision support systemfebrile neutropeniafebrile neutropenia guidelineshematological malignancyhematopoietic stem cell transplantationsolid tumors

Identifiers

PMID39335006
PMCPMC11429046

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.