Evidence map›Paper›PMID 39334978›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Novel Antimicrobial Agents Based on Zinc-Doped Hydroxyapatite Loaded with Tetracycline.

Simona Liliana Iconaru, Daniela Predoi, Carmen Steluta Ciobanu, Catalin Constantin Negrila, Roxana Trusca, Steinar Raaen, Krzysztof Rokosz, Liliana Ghegoiu, Monica Luminita Badea, Carmen Cimpeanu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Simona Liliana IconaruNational Institute of Materials Physics, Atomistilor Street, No. 405A, 077125 Magurele, Romania.ORCID 0000-0002-9139-5903
Daniela PredoiNational Institute of Materials Physics, Atomistilor Street, No. 405A, 077125 Magurele, Romania.
Carmen Steluta CiobanuNational Institute of Materials Physics, Atomistilor Street, No. 405A, 077125 Magurele, Romania.ORCID 0000-0002-6044-4311
Catalin Constantin NegrilaNational Institute of Materials Physics, Atomistilor Street, No. 405A, 077125 Magurele, Romania.
Roxana TruscaNational Centre for Micro and Nanomaterials, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Steinar RaaenDepartment of Physics, Norwegian University of Science and Technology (NTNU), Realfagbygget E3-124 Høgskoleringen 5, NO 7491 Trondheim, Norway.
Krzysztof RokoszFaculty of Electronics and Computer Science, Koszalin University of Technology, Śniadeckich 2, PL 75-453 Koszalin, Poland.ORCID 0000-0002-1040-7213
Liliana GhegoiuNational Institute of Materials Physics, Atomistilor Street, No. 405A, 077125 Magurele, Romania.
Monica Luminita BadeaFaculty of Horticulture, University of Agronomic Sciences and Veterinary Medicine, 59 Marasti Boulevard, 011464 Bucharest, Romania.
Carmen CimpeanuFaculty of Land Reclamation and Environmental Engineering, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Boulevard, 011464 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we present for the first time the development of zinc-doped hydroxyapatite enriched with tetracycline (ZnHApTe) powders and provide a comprehensive evaluation of their physico-chemical and biological properties. Various techniques such as X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR) were used for the sample's complex evaluation. Moreover, the biocompatibility of zinc-doped hydroxyapatite (ZnHAp) and ZnHApTe nanoparticles was evaluated with the aid of human fetal osteoblastic cells (hFOB 1.19 cell line). The results of the biological assays suggested that these nanoparticles hold great promise as potential candidates for the future development of novel biocompatible and antimicrobial agents for biomedical applications. The antimicrobial properties of the ZnHAp and ZnHApTe nanoparticles were assessed using the standard reference microbial strains

Indexed as

biomedical applicationscompositionhydroxyapatitein vitro biological studiestetracyclinezinc

Identifiers

PMID39334978
PMCPMC11428947

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.