Evidence map›Paper›PMID 39334653›Full record

ArticleChildren (Basel, Switzerland)2024

Association of Right Ventricular Dysfunction with Risk of Neurodevelopmental Impairment in Infants with Pulmonary Hypertension.

Rossana Romero Orozco, Tazuddin A Mohammed, Kerri Carter, Shaaron Brown, Stephen Miller, Roy T Sabo, Meredith Campbell Joseph, Uyen Truong, Megha Nair, Victoria Anderson and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rossana Romero OrozcoDepartment of Pediatrics, Children's Hospital of Richmond at VCU, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0009-0007-9754-0060
Tazuddin A MohammedDepartment of Pediatrics, Children's Hospital of Richmond at VCU, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0001-5358-0377
Kerri CarterDepartment of Pediatrics, Children's Hospital of Richmond at VCU, Virginia Commonwealth University, Richmond, VA 23298, USA.
Shaaron BrownDepartment of Physical Therapy, Children's Hospital of Richmond at VCU, Virginia Commonwealth University, Richmond, VA 23298, USA.
Stephen MillerVirginia Commonwealth University School of Medicine, Richmond, VA 23298, USA.ORCID 0000-0002-7561-3114
Roy T SaboDepartment of Biostatistics, School of Public Health, Virginia Commonwealth University, Richmond, VA 23219, USA.
Meredith Campbell JosephDepartment of Pediatrics, UF Health Shands Children's Hospital, University of Florida, Gainesville, FL 32610, USA.
Uyen TruongDepartment of Pediatrics, Children's National Hospital, Washington, DC 20010, USA.
Megha NairVirginia Commonwealth University School of Medicine, Richmond, VA 23298, USA.
Victoria AndersonSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Jie XuVirginia Commonwealth University School of Medicine, Richmond, VA 23298, USA.
Judith A VoynowDepartment of Pediatrics, Children's Hospital of Richmond at VCU, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0002-2437-2859
Karen D Hendricks-MuñozDepartment of Pediatrics, Children's Hospital of Richmond at VCU, Virginia Commonwealth University, Richmond, VA 23298, USA.

Funding

Wright Regional Center for Clinical and Translational ScienceUM1TR004360 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI FREDERICK Gerard MOELLER · 2023 to 2026
$16.3M
NCATS NIH HHS UM1 TR004360NCATS NIH HHS UM1TR004360
6 · The paper itself

Abstract

(1) Background: Pulmonary hypertension (PH) increases pulmonary vascular resistance and right ventricular (RV) afterload. Assessment of RV systolic function in PH using RV fractional area change (RV FAC) as a marker directly correlates with mortality and the need for extracorporeal membrane oxygenation (ECMO). However, few studies have assessed neurodevelopmental outcomes. We hypothesize that cardiac RV systolic dysfunction with lower RV FAC is associated with worse neurodevelopmental impairment (NI). (2) Methods: Retrospective study of 42 subjects with PH to evaluate neurodevelopmental outcomes in the first two years of life based on (i) subjective assessment of RV systolic function and (ii) RV FAC, a specific echocardiographic marker for RV function. (3) Results: Subjects from the initial study cohort (

Indexed as

neurodevelopmental impairment (NI)pulmonary hypertension (PH)pulmonary vascular resistance (PVR)right ventricle (RV)

Identifiers

PMID39334653
PMCPMC11430681

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.