Evidence map›Paper›PMID 39334648›Full record

ArticleChildren (Basel, Switzerland)2024

Transcutaneous Spinal Cord Stimulation Enables Recovery of Walking in Children with Acute Flaccid Myelitis.

Elizabeth Neighbors, Lia Brunn, Agostina Casamento-Moran, Rebecca Martin

Registry-linked trialAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07615686 (Transcutaneous Spinal Cord Stimulation to Improve Strength and Gait in Children With Spina Bifida), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07615686 narecruitingnot on this mapstarted 2026, after this paper: background citation

Transcutaneous Spinal Cord Stimulation to Improve Strength and Gait in Children With Spina Bifida

TypeinterventionalSponsorBailey PetersenRan2026 to 2029Enrolled20ConditionsSpina Bifida, MyelomeningoceleArmsTranscutaneous stimulator
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elizabeth NeighborsInternational Center for Spinal Cord Injury, Hugo W. Moser Research Institute at Kennedy Krieger Institute, Baltimore, MD 21205, USA.
Lia BrunnInternational Center for Spinal Cord Injury, Hugo W. Moser Research Institute at Kennedy Krieger Institute, Baltimore, MD 21205, USA.
Agostina Casamento-MoranInternational Center for Spinal Cord Injury, Hugo W. Moser Research Institute at Kennedy Krieger Institute, Baltimore, MD 21205, USA.
Rebecca MartinInternational Center for Spinal Cord Injury, Hugo W. Moser Research Institute at Kennedy Krieger Institute, Baltimore, MD 21205, USA.

Funding

Golstein Grant for Innovation from the Kennedy Krieger Foundation unsure
6 · The paper itself

Abstract

backgroundLimited research exists for use of transcutaneous spinal stimulation (TSS) in pediatric spinal cord injuries (SCI) to improve walking outcomes, especially in children diagnosed with SCI secondary to acute flaccid myelitis (AFM).

objectiveThis case series demonstrates the feasibility and efficacy of TSS paired with gait training in children diagnosed with AFM.

methodsA total of 4 participants diagnosed with incomplete SCI secondary to AFM completed 22, 2-h therapy sessions over 5-8 weeks. TSS paired with body weight-supported treadmill training (BWSTT) was provided for the first 30 min of each session. Changes in walking function were assessed through the 6 min walk test (6MWT), Timed Up and Go (TUG), 10 m walk test (10MWT), and walking index for spinal cord injury II (WISCI-II). To assess safety and feasibility, pain, adverse events, and participant and therapist exertion were monitored.

resultsAll participants tolerated the TSS intervention without pain or an adverse response. Changes in the 6MWT exceeded the minimal clinically important difference (MCID) for three participants and WISCI-II exceeding the minimal detectable change (MDC) for two of the participants.

conclusionsThese results demonstrate that TSS is a safe and clinically feasible intervention for pediatric patients with AFM and may supplement gait-based interventions to facilitate improvements in walking function.

Indexed as

acute flaccid myelitisfunctional outcomesgaitneuromodulationpediatricsrecoveryrehabilitationspinal cord injurytranscutaneous spinal cord stimulation

Identifiers

PMID39334648
PMCPMC11430423

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.