Evidence map›Paper›PMID 39334438›Full record

ArticleTrials2024

OPTimising MEDicine information handover after Discharge (OPTMED-D): protocol for development of a multifaceted intervention and stepped wedge cluster randomised controlled trial.

Laetitia Hattingh, Melissa T Baysari, Holly Foot, Tin Fei Sim, Gerben Keijzers, Mark Morgan, Ian Scott, Richard Norman, Faith Yong, Barbara Mullan and 3 more

Erratum issuedAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Laetitia HattinghAllied Health Research, Gold Coast Health, Southport, QLD, 4215, Australia. laetitia.hattingh@health.qld.gov.au.ORCID http://orcid.org/0000-0002-4553-743X
Melissa T BaysariBiomedical Informatics and Digital Health, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, 2050, Australia.ORCID http://orcid.org/0000-0003-1645-9126
Holly FootSchool of Pharmacy, The University of Queensland, Brisbane, QLD, 4102, Australia.ORCID http://orcid.org/0000-0002-5993-9050
Tin Fei SimCurtin Medical School, Curtin University, Bentley, WA, 6102, Australia.ORCID http://orcid.org/0000-0003-0068-5006
Gerben KeijzersEmergency Department, Gold Coast Health, Southport, QLD, 4215, Australia.ORCID http://orcid.org/0000-0003-1100-4552
Mark MorganFaculty of Health Sciences and Medicine, Bond University, Gold Coast, QLD, 4229, Australia.ORCID http://orcid.org/0000-0001-7749-2427
Ian ScottMetro South Digital Health and Informatics, Princess Alexandra Hospital, Woolloongabba, QLD, 4102, Australia.ORCID http://orcid.org/0000-0002-7596-0837
Richard NormanSchool of Population Health, Curtin University, Bentley, WA, 6102, Australia.ORCID http://orcid.org/0000-0002-3112-3893
Faith YongRural Clinical School, Faculty of Medicine, The University of Queensland, Brisbane, QLD, 4350, Australia.ORCID http://orcid.org/0000-0002-4878-7565
Barbara MullanSchool of Population Health, Curtin University, Bentley, WA, 6102, Australia.ORCID http://orcid.org/0000-0002-0177-8899
Claire JacksonGeneral Practice and Primary Care Reform, The University of Queensland, Brisbane, QLD, 4072, Australia.ORCID http://orcid.org/0000-0003-1177-1380
Leslie E OldfieldSchool of Pharmacy, The University of Queensland, Brisbane, QLD, 4102, Australia.ORCID http://orcid.org/0000-0003-1313-5580
Elizabeth ManiasSchool of Nursing and Midwifery, Monash University, Melbourne, VIC, 3800, Australia.ORCID http://orcid.org/0000-0002-3747-0087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGeneral practitioners (GP) and community pharmacists need information about hospital discharge patients' medicines to continue their management in the community. This necessitates effective communication, collaboration, and reliable information-sharing. However, such handover is inconsistent, and whilst digital systems are in place to transfer information at transitions of care, these systems are passive and clinicians are not prompted about patients' transitions. There are also gaps in communication between community pharmacists and GPs. These issues impact patient safety, leading to hospital readmissions and increased healthcare costs.

methodsA three-phased, multi-method study design is planned to trial a multifaceted intervention to reduce 30-day hospital readmissions. Phase 1 is the co-design of the intervention with stakeholders and end-users; phase 2 is the development of the intervention; phase 3 is a stepped wedge cluster randomised controlled trial with 20 clusters (community pharmacies). Expected intervention components will be a hospital pharmacist navigator, primary care medication management review services, and a digital solution for information sharing. Phase 3 will recruit 10 patients per pharmacy cluster/month to achieve a sample size of 2200 patients powered to detect a 5% absolute reduction in unplanned readmissions from 10% in the control group to 5% in the intervention at 30 days. The randomisation and intervention will occur at the level of the patient's nominated community pharmacy. Primary analysis will be a comparison of 30-day medication-related hospital readmissions between intervention and control clusters using a mixed effects Poisson regression model with a random effect for cluster (pharmacy) and a fixed effect for each step to account for secular trends.

trial registrationThis trial is registered with the Australian New Zealand Clinical Trials Registry: ACTRN12624000480583p , registered 19 April 2024.

Indexed as

Community Pharmacy ServicesPatient DischargePatient HandoffPatient ReadmissionPharmacistsRandomized Controlled Trials as TopicContinuity of Patient CareGeneral PractitionersHumansMedication ReconciliationTime FactorsCommunity pharmacyHospital dischargeMedication-related harmMedicine handoverTransition of care

Identifiers

PMID39334438
PMCPMC11428332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.