Evidence map›Paper›PMID 39334351›Full record

ArticleCancer cell international2024

TRPV2 calcium channel promotes breast cancer progression potential by activating autophagy.

Qing Li, Huixian Li, Ruiwen Zhu, William Chi Shing Cho, Xiaoqiang Yao, Fung Ping Leung, Gary Tse, Lai Kwok Leung, Wing Tak Wong

Abstract read
In one paragraph

Article in Cancer cell international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. PIEZO2 in tumors: from mechanobiological switches to activity-targeted therapies.Journal of experimental & clinical cancer research : CR · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qing Li *School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, 999077, China.
Huixian Li *School of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, 999077, China.
Ruiwen ZhuSchool of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, 999077, China.
William Chi Shing ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR, 999077, China.
Xiaoqiang YaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, 999077, China.
Fung Ping LeungSchool of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, 999077, China.
Gary TseSchool of Nursing and Health Studies, Hong Kong Metropolitan University, Hong Kong, 999077, China.
Lai Kwok LeungSchool of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, 999077, China. laikleung@yahoo.com.
Wing Tak WongSchool of Life Sciences, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, 999077, China. jack_wong@cuhk.edu.hk.

Funding

National Natural Science Foundation of China 81970423Research Grants Council of Hong Kong 24163117
6 · The paper itself

Abstract

Breast cancer, the most prevalent and aggressive tumor affecting women, requires identification of disease determinants to facilitate the development of effective therapeutic strategies. Transient receptor potential vanilloid 2 (TRPV2), an ion channel highly permeable for calcium (Ca

Indexed as

AMPKAutophagyBreast cancerCalcium channelCaMKKβTRPV2ULK1

Identifiers

PMID39334351
PMCPMC11438410

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.