Evidence map›Paper›PMID 39334320›Full record

SynthesisEnvironmental health : a global access science source2024

Prenatal exposure to air pollution and maternal and fetal thyroid function: a systematic review of the epidemiological evidence.

Catherine O'Donnell, Erin J Campbell, Sabrina McCormick, Susan C Anenberg

Abstract readSystematic Review
In one paragraph

Synthesis in Environmental health : a global access science source, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Catherine O'DonnellDepartment of Environmental and Occupational Health, The George Washington University, Washington, District of Columbia, USA. catherineod@gwu.edu.
Erin J CampbellDepartment of Environmental and Occupational Health, The George Washington University, Washington, District of Columbia, USA.
Sabrina McCormickResilience Creative, New York, NY, USA.
Susan C AnenbergDepartment of Environmental and Occupational Health, The George Washington University, Washington, District of Columbia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExposure to ambient air pollution is a top risk factor contributing to the global burden of disease. Pregnant persons and their developing fetuses are particularly susceptible to adverse health outcomes associated with air pollution exposures. During pregnancy, the thyroid plays a critical role in fetal development, producing thyroid hormones that are associated with brain development. Our objective is to systematically review recent literature that investigates how prenatal exposure to air pollution affects maternal and fetal thyroid function.

methodsFollowing the Navigation Guide Framework, we systematically reviewed peer-reviewed journal articles that examined prenatal exposures to air pollution and outcomes related to maternal and fetal thyroid function, evaluated the risk of bias for individual studies, and synthesized the overall quality and strength of the evidence.

resultsWe found 19 studies that collected data on pregnancy exposure windows spanning preconception to full term from 1999 to 2020 across nine countries. Exposure to fine particulate matter (PM

conclusionTo improve the quality of the body of evidence, future research should seek to enhance exposure assessment methods by integrating personal monitoring and high-quality exposure data (e.g., using spatiotemporally resolved satellite observations and statistical modeling) and outcome assessment methods by measuring a range of thyroid hormones throughout the course of pregnancy.

Indexed as

Air PollutionMaternal ExposurePrenatal Exposure Delayed EffectsThyroid GlandFemaleFetusHumansParticulate MatterPregnancyThyroid HormonesParticulate MatterThyroid HormonesAir pollutionFetalMaternalPrenatalThyroid function

Identifiers

PMID39334320
PMCPMC11438274

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.