Evidence map›Paper›PMID 39334111›Full record

ArticleBMC health services research2024

Awareness of, willingness to use, and experiences with Pre-exposure prophylaxis among youth in Nigeria.

Titilola Gbaja-Biamila, Chisom Obiezu-Umeh, Ucheoma Nwaozuru, Nora E Rosenberg, Mesoma Igbokwe, David Oladele, Adesola Z Musa, Ifeoma Idigbe, Donaldson Conserve, Suzanne Day and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in BMC health services research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04070287 (Innovative Tools to Expand HIV Self-Testing), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04070287 early_phase1completednot on this map

Innovative Tools to Expand HIV Self-Testing

TypeinterventionalSponsorWashington University School of MedicineRan2019 to 2020Enrolled388ConditionsHIV/AIDS, Sexually Transmitted DiseasesArmsSMART Pack, Luv Box, Bili Vibes, BeterDoc, IUNGO
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Titilola Gbaja-BiamilaWashington University in St Louis, St Louis, USA. g.titilola@wustl.edu.
Chisom Obiezu-UmehNorthwestern University, Chicago, USA.
Ucheoma NwaozuruWake Forest School of Medicine, Winston-Salem, USA.
Nora E RosenbergUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Mesoma IgbokweRochester General Hospital, New York, USA.
David OladeleNigerian Institute of Medical Research, Lagos, Nigeria.
Adesola Z MusaNigerian Institute of Medical Research, Lagos, Nigeria.
Ifeoma IdigbeNigerian Institute of Medical Research, Lagos, Nigeria.
Donaldson ConserveGeorge Washington University, Washington, USA.
Suzanne DayUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kadija TahlilUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jason OngMonash University, Melbourne, Australia.
Kathryn MuessigFlorida State University, Tallahassee, USA.
Susan NkengasongLondon School of Hygiene & Tropical Medicine, London, UK.
Hong XianSaint Louis University, St Louis, USA.
Joseph D TuckerUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Oliver EzechiNigerian Institute of Medical Research, Lagos, Nigeria.
Juliet IwelunmorWashington University in St Louis, St Louis, USA.

Funding

Training in Sexually Transmitted Infections and HIVT32AI007001 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SENA-SOBERANO, ARLENE C. · 1985 to 2025
$10.9M
ITEST: Innovative Tools to Expand Youth-Friendly HIV Self-TestingUG3HD096929 · NICHD · SAINT LOUIS UNIVERSITY · PI EZECHI, OLIVER CHUKWUJEKWU, IWELUNMOR, JULIET · 2018 to 2019
$2.3M
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) UG3HD096929National Institute of Allergy and Infectious Disease (NIAID) T32AI007001NIAID NIH HHS T32 AI007001NICHD NIH HHS UG3 HD096929
6 · The paper itself

Abstract

backgroundYouth (ages 14-24) in Nigeria have disproportionately high rates of new HIV infection. Pre-exposure prophylaxis could substantially reduce new infections among youth but has not been scaled up. This cross-sectional study aimed to assess Pre-exposure prophylaxis awareness, willingness to use, and prior use of Pre-exposure prophylaxis among youth in Nigeria.

methodsThis is a secondary analysis of cross-sectional data from a quasi-experimental pilot study (clinical trial NCT04070287). The analysis focused on Pre-exposure prophylaxis awareness, willingness to use, and prior use among 324 youth recruited between September 2019 to March 2020. Descriptive statistics were calculated as frequencies and percentages for categorical variables and means and standard deviations for continuous variables.

resultsOf the 324 participants, the mean age and standard deviation were 21.17 (± 2.20) years. The majority were 20-24 years old (75.9%) and male (57.7%). Only 30.7% used condoms consistently over three months. Regarding Pre-exposure prophylaxis awareness and willingness, 62.6% had never heard of Pre-exposure prophylaxis, and 158 (50.1%) reported willingness to use Pre-exposure prophylaxis. Only 10 (3.2%) reported having used Pre-exposure prophylaxis.

conclusionNigerian youth have low awareness of and prior use of Pre-exposure prophylaxis. Given the gap between prior use and willingness to use Pre-exposure prophylaxis, our findings suggest missed opportunities to prevent new HIV infections among youth in Nigeria. Efforts to increase awareness and uptake of Pre-exposure prophylaxis among this population should consider youth-led Pre-exposure prophylaxis outreach efforts and effectively communicate the benefits of Pre-exposure prophylaxis to this population.

trial registrationNCT04070287, the Date of registration of the trial is 20-07-2019.

Indexed as

Health Knowledge, Attitudes, PracticeHIV InfectionsPre-Exposure ProphylaxisAdolescentAnti-HIV AgentsCross-Sectional StudiesFemaleHumansMaleNigeriaPatient Acceptance of Health CarePilot ProjectsYoung AdultAnti-HIV AgentsAntiretroviral therapyHIVPre-exposure prophylaxisYouth

Identifiers

PMID39334111
PMCPMC11428911

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.