Evidence map›Paper›PMID 39333943›Full record

ArticleBMC ophthalmology2024

Variations in anterior segment parameters among different phenotypes of polycystic ovary syndrome.

Fatma Sumer, Beril Gurlek, Elif Yildiz, Feyzahan Uzun, Mehmet Gokhan Aslan, Sabri Colak, Hasan Akgoz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatma SumerRecep Tayyip Erdogan University, Faculty of Medicine, Department of Ophthalmology, Rize, Turkey. fatmasumer_@hotmail.com.ORCID http://orcid.org/0000-0002-4146-8190
Beril GurlekRecep Tayyip Erdogan University, Faculty of Medicine, Department of Gynaecology and Obstetrics, Rize, Turkey.ORCID http://orcid.org/0000-0002-4050-3193
Elif YildizIstanbul Gazıosmanpasa Training and Research Hospital, Istanbul G.O.P Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8396-5542
Feyzahan UzunRecep Tayyip Erdogan University, Faculty of Medicine, Department of Ophthalmology, Rize, Turkey.ORCID http://orcid.org/0000-0002-3050-0714
Mehmet Gokhan AslanRecep Tayyip Erdogan University, Faculty of Medicine, Department of Ophthalmology, Rize, Turkey.ORCID http://orcid.org/0000-0002-3250-1606
Sabri ColakRecep Tayyip Erdogan University, Faculty of Medicine, Department of Gynaecology and Obstetrics, Rize, Turkey.ORCID http://orcid.org/0000-0002-4301-6104
Hasan AkgozRecep Tayyip Erdogan University, Faculty of Medicine, Department of Ophthalmology, Rize, Turkey.ORCID http://orcid.org/0000-0003-1115-8359

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of this study was to evaluate anterior segment parameters across various phenotypes of polycystic ovary syndrome (PCOS), considering body mass index (BMI), serum estradiol and testosterone levels. MATERIALS AND

methodsThis prospective study included 116 women with PCOS, with each of the four distinct phenotype comprising 29 women. Additionally, 29 healthy women were included in the control group. All participants underwent comprehensive ophthalmologic examinations, including intraocular pressure (IOP) measurements. Anterior segment parameters, such as central corneal thickness (CCT), axial length (AL), aqueous depth (AD), anterior chamber depth (ACD), and lens thickness (LT) were measured using optic biometry. Endothelial cell density (ECD) was assessed using non-contact specular microscopy. The BMI was calculated, and serum levels of estradiol and testosterone were noted.

resultsIOP was found to be significantly higher (p = 0.003) and CCT was significantly thicker (p = 0.004) in all phenotypes of PCOS compared to the control group. BMI, serum estradiol and free testosterone were found to correlate with both IOP and CCT. AL, AD, ACD and LT values showed no significant differences compared to the control group. Although ECD tend to be higher in the PCOS phenotypes, this difference was not statistically significant (p > 0.05).

conclusionGiven our findings that CCT and IOP are significantly elevated in PCOS phenotypes. PCOS should be considered as an important factor when evaluating female patients for anterior segment diseases and glaucoma.

Indexed as

Anterior Eye SegmentBody Mass IndexIntraocular PressurePhenotypePolycystic Ovary SyndromeTestosteroneAdultAxial Length, EyeBiometryEstradiolFemaleHumansProspective StudiesYoung AdultEstradiolTestosteroneAnterior segment parametersCentral corneal thicknessIntraocular pressurePolycystic ovary syndrome

Identifiers

PMID39333943
PMCPMC11437628

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.