Evidence map›Paper›PMID 39333938›Full record

ArticleBMC public health2024

Disparities in age and gender-specific SARS-CoV-2 diagnostic testing trends: a retrospective study from Pakistan.

Najia Karim Ghanchi, Kiran Iqbal Masood, Muhammad Farrukh Qazi, Shahira Shahid, Asghar Nasir, Syed Faisal Mahmood, Zeeshan Ansar, Muhammad Imran Nisar, Zahra Hasan

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Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Najia Karim GhanchiDepartment of Pathology and Laboratory Medicine, Aga Khan University, Stadium Road, P.O.Box 3500, Karachi, 74800, Pakistan.
Kiran Iqbal MasoodDepartment of Pathology and Laboratory Medicine, Aga Khan University, Stadium Road, P.O.Box 3500, Karachi, 74800, Pakistan.
Muhammad Farrukh QaziDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Shahira ShahidDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Asghar NasirDepartment of Pathology and Laboratory Medicine, Aga Khan University, Stadium Road, P.O.Box 3500, Karachi, 74800, Pakistan.
Syed Faisal MahmoodDepartment of Medicine, Aga Khan University, Karachi, Pakistan.
Zeeshan AnsarDepartment of Pathology and Laboratory Medicine, Aga Khan University, Stadium Road, P.O.Box 3500, Karachi, 74800, Pakistan.
Muhammad Imran NisarDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Zahra HasanDepartment of Pathology and Laboratory Medicine, Aga Khan University, Stadium Road, P.O.Box 3500, Karachi, 74800, Pakistan. zahra.hasan@aku.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPakistan reported 1.57 million COVID-19 cases between 2020 and 2022, based on approximately 30.6 million SARS-CoV-2 RT-PCR (reverse-transcription polymerase chain reaction) tests conducted. This study utilized data from one of the largest in-country testing facilities, Aga Khan University Hospital (AKUH) in Karachi, Pakistan, to explore gender and age-related in RT-PCR testing patterns.

methodsWe conducted a retrospective review of SARS-CoV-2 RT-PCR test data extracted from AKUH clinical laboratory records between February 2020 and February 2022. Gender and age distributions were examined in the context of testing patterns across the period. Multivariate regression models assessed independent associations between COVID-19 positivity and key variables.

resultsWe reviewed 470,249 RT-PCR tests, finding that most tests were in those aged 21-40 years (48.1%). Overall, COVID-19 test positivity was 20.6%. In all, 57.7% were performed for males, predominant amongst those tested across all age groups and waves. Females had significantly lower odds of testing positive for COVID-19 (OR: 0.9; 95% CI: 0.9-1.0). However, when adjusted for gender, age and pandemic phases, the positivity rates between males and females were the same. The odds of a positive result increased significantly with age; individuals aged > 80 years had 2.5 times higher odds of testing positive than those aged 0-10 years (aOR 2.5, 95% CI 2.3-2.7).

conclusionsThe analysis indicates a consistent male dominance in COVID-19 testing, with higher positivity rates in older age groups. Our study highlight the importance of examining demographic characteristics in disease associated data especially, representation of females amongst cohorts.

Indexed as

COVID-19SARS-CoV-2AdolescentAdultAgedAged, 80 and overAge DistributionAge FactorsChildChild, PreschoolCOVID-19 Nucleic Acid TestingCOVID-19 TestingFemaleHealthcare DisparitiesHumansInfantAgeCOVID-19GenderPositivityRT-PCR

Identifiers

PMID39333938
PMCPMC11438081

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.