Cooperative chemoenzymatic and biocatalytic cascades to access chiral sulfur compounds bearing C(sp

Fei Zhao, Ariane Mattana, Ruqaiya Alam, Sarah L Montgomery, Akash Pandya, Fabrizio Manetti, Beatriz Dominguez, Daniele Castagnolo

Abstract read

PubMed Full text at PMC Publisher

In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

Research and Developments of Heterogeneous Catalytic Technologies.Molecules (Basel, Switzerland) · 2025
Review
Unlocking Lactonase Enzymes as Biocatalysts for the Deracemisation of Chiral γ-Thiolactones.Angewandte Chemie (International ed. in English) · 2025
Article
Asymmetric Enantio-complementary Synthesis of Thioethers via Ene-Reductase-Catalyzed C-C Bond Formation.Journal of the American Chemical Society · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fei ZhaoDepartment of Chemistry, University College London, London, UK.ORCID http://orcid.org/0000-0003-1841-4466

Ariane MattanaDepartment of Chemistry, University College London, London, UK.

Ruqaiya AlamDepartment of Chemistry, University College London, London, UK.ORCID http://orcid.org/0009-0002-5066-9231

Sarah L MontgomeryJohnson Matthey, Cambridge, UK.ORCID http://orcid.org/0000-0003-3703-4338

Akash PandyaJohnson Matthey, Cambridge, UK.

Fabrizio ManettiDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.ORCID http://orcid.org/0000-0002-9598-2339

Beatriz DominguezJohnson Matthey, Cambridge, UK. beatriz.dominguez@matthey.com.

Daniele CastagnoloDepartment of Chemistry, University College London, London, UK. d.castagnolo@ucl.ac.uk.ORCID http://orcid.org/0000-0002-7517-5732

Funding

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 838326RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/T008709/1

6 · The paper itself

Abstract

Biocatalysis has been widely employed for the generation of carbon-carbon/heteroatom stereocentres, yet its application in chiral C(sp

Identifiers

PMID39333478

DOI10.1038/s41467-024-52608-8

PMCPMC11436715

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.