Evidence map›Paper›PMID 39333461›Full record

ArticleNeurosurgical review2024

A multicenter study of clinical outcomes and volumetric trends in suspected microprolactinomas.

Christopher S Hong, Jeremi Chabros, John L Kilgallon, Jakob V E Gerstl, Chady Omara, Richard Drexler, Jörg Flitsch, Franz L Ricklefs, Alice S Ryba, Diego Mazzatenta and 4 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Neurosurgical review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Christopher S HongDepartment of Neurosurgery, Computational Neurosciences Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Street, BTM 4, Boston, MA, 02115, USA. chong6@mgb.org.
Jeremi ChabrosDepartment of Neurosurgery, Computational Neurosciences Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Street, BTM 4, Boston, MA, 02115, USA.
John L KilgallonDepartment of Neurosurgery, Computational Neurosciences Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Street, BTM 4, Boston, MA, 02115, USA.
Jakob V E GerstlDepartment of Neurosurgery, Computational Neurosciences Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Street, BTM 4, Boston, MA, 02115, USA.
Chady OmaraDepartment of Neurosurgery, Computational Neurosciences Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Street, BTM 4, Boston, MA, 02115, USA.
Richard DrexlerDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Jörg FlitschDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Franz L RicklefsDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Alice S RybaDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Diego MazzatentaIRCCS Institute of Neurological Sciences of Bologna, Bologna, Italy.
Federica GuaraldiIRCCS Institute of Neurological Sciences of Bologna, Bologna, Italy.
Carleton E CorralesDepartment of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Le MinDivision of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Timothy R SmithDepartment of Neurosurgery, Computational Neurosciences Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Street, BTM 4, Boston, MA, 02115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of pituitary microprolactinomas is often obscured by relatively low levels of elevated prolactin compared to macroprolactinomas. This may lead to varying patterns of medical therapy versus observation. We sought to correlate prolactin levels in suspected microprolactinomas with tumor volumes and clinical outcomes. This was a multicenter retrospective study of patients with pituitary microadenomas with baseline prolactin levels > 18ng/ml for males and > 30ng/ml for females. A linear-mixed model was used to depict changes in tumor volume over time. There were 65 patients with a mean tumor volume of 95.9mm

Indexed as

Pituitary NeoplasmsProlactinProlactinomaTumor BurdenAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultProlactinMicroadenomaPituitaryProlactinProlactinoma

Identifiers

PMID39333461

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.