Evidence map›Paper›PMID 39333028›Full record

ArticleThe Australian & New Zealand journal of obstetrics & gynaecology2025

Significant kidney disease in pregnancy: Feasibility and outcomes of a national population-based study using the Australasian Maternity Outcomes Surveillance System.

Shilpanjali Jesudason, Nadom Safi, Zhuoyang Li, Mark Brown, William Hague, Angela Makris, Stephen McDonald, Michael J Peek, Elizabeth Sullivan

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Article in The Australian & New Zealand journal of obstetrics & gynaecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Shilpanjali JesudasonPregnancy and Kidney Research Australia, Central Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital and Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0001-9695-0761
Nadom SafiSchool of Medicine and Public Health, Central Coast Clinical School, The University of Newcastle, Gosford, New South Wales, Australia.ORCID 0000-0001-8473-0980
Zhuoyang LiCollege of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.
Mark BrownDepartment Renal Medicine and Medicine, St. George Hospital and University of New South Wales, Sydney, New South Wales, Australia.
William HagueRobinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia.ORCID 0000-0002-5355-2955
Angela MakrisDepartment of Renal Medicine, Liverpool Hospital, Sydney, New South Wales, Australia.
Stephen McDonaldPregnancy and Kidney Research Australia, Central Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital and Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.
Michael J PeekNepean Clinical School, College of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Elizabeth SullivanCollege of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.

Funding

Royal Adelaide Hospital 2016
6 · The paper itself

Abstract

backgroundCurrent understanding of clinical practice and care for maternal kidney disease in pregnancy in Australia is hampered by limitations in available renal-specific datasets.

aimsTo capture the epidemiology, management, and outcomes of women with significant kidney disease in pregnancy and demonstrate feasibility of a national cohort study approach. MATERIALS AND

methodsAn Australian prospective study (2017-2018) using a new kidney disease-specific survey within the Australasian Maternity Outcomes Surveillance System (AMOSS). Women who gave birth with acute kidney injury (AKI), advanced chronic kidney disease (CKD), dialysis dependence or a kidney transplant were included. Demographic data, renal and obstetric management, and perinatal outcomes were collected.

resultsAmong 58 case notifications from 12 hospitals in five states, we included 23 cases with kidney transplant (n = 12), pre-existing CKD (n = 8), newly diagnosed CKD (n = 2) and dialysis (n = 1). No cases of AKI were reported. Reporting rates were better in states with study investigators and, overall, cases were likely under-reported. Nearly 35% of women had a non-delivery-related antenatal admission. Nephrology involvement was 78.3% during pregnancy and 91% post-partum. Adverse events were increased, including pre-eclampsia (21.7%), and preterm birth (60.9%). Women had high rates of aspirin (82.6%) and antihypertensive (73.9%) use, indwelling catheter for labour/delivery (65.2%), caesarean delivery (60.9%), and blood transfusion (21.7%).

conclusionsThis first-ever Australian prospective study of significant kidney diseases in pregnancy provided novel insights into renal-specific clinical patterns and practices. However, under-reporting was likely. Future studies need to overcome the challenges of case identification and data collection burden.

Indexed as

Acute Kidney InjuryPregnancy ComplicationsRenal Insufficiency, ChronicAdultAustraliaFeasibility StudiesFemaleHumansKidney TransplantationPregnancyPregnancy OutcomeProspective StudiesRenal DialysisYoung Adultacute kidney injurychronic kidney diseasekidney failureobstetricpregnancy

Identifiers

PMID39333028
PMCPMC12099190

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