Evidence map›Paper›PMID 39332627›Full record

ArticleJournal of vascular surgery. Venous and lymphatic disorders2025

Optimizing strategies for lymphaticovenular anastomosis in lower secondary extremity lymphedema.

Liqi Yi, YanFei Jiang, Lei Xu, Minxiang Zheng, Youmao Zheng, Junbo Liang, Chong Liu

Abstract read
In one paragraph

Article in Journal of vascular surgery. Venous and lymphatic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liqi YiTaizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University, Taizhou, China; Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, China.
YanFei JiangTaizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University, Taizhou, China; Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, China.
Lei XuTaizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University, Taizhou, China; Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, China.
Minxiang ZhengTaizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University, Taizhou, China; Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, China.
Youmao ZhengTaizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University, Taizhou, China; Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, China.
Junbo LiangTaizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University, Taizhou, China; Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, China.
Chong LiuTaizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University, Taizhou, China; Enze Hospital, Taizhou Enze Medical Center (Group), Taizhou, China. Electronic address: liu_chong02@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLymphovenous anastomosis (LVA) has become an increasingly common treatment for patients with secondary extremity lymphedema. The objective of this study was to optimize strategies for lower secondary extremity lymphedema using LVA techniques, with the aim of enhancing patient outcomes.

methodsWe conducted a retrospective analysis of 121 patients who underwent LVA at Taizhou Hospital of Zhejiang Province from January 2020 to December 2023. Preoperative and postoperative assessments included intraoperative observations, functional parameters, and clinical outcomes. The efficacy of LVA was evaluated based on circumferential reduction, quality of life improvements (Lymphoedema Quality of Life Questionnaire), and postoperative complications.

resultsThis study enrolled 121 patients with lower secondary extremity lymphedema, with an average age of 58.19 years. The results revealed significant associations between incision depth, lymphatic vessel size, the number of LVAs performed, and the number of incisions per patient, all of which correlated with postoperative volume reduction. The resulted analysis that identified optimal incision depths of 10 to 15 mm, lymphatic vessel size of 0.4 to 0.6 mm, and a recommended number of 6 to 8 LVAs. After LVA, there was a marked improvement in patient quality of life, with particularly notable enhancements in functionality and appearance.

conclusionsThis study's findings optimizing the strategy for LVA surgery recommend the depth of incision, the size of lymphatic vessels, and the number of anastomoses to improve the quality of life and limb volume in patients with secondary lymphedema of the lower limbs.

Indexed as

Anastomosis, SurgicalLower ExtremityLymphatic VesselsLymphedemaQuality of LifeAdultAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeVeinsLower extremity lymphedemaLVA strategiesLymphaticovenous anastomosis

Identifiers

PMID39332627
PMCPMC11764253

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.