Evidence map›Paper›PMID 39331827›Full record

ArticleRevista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)2025

Parenthood and all-cause mortality in older adults with schizophrenia: a multicenter 5-year prospective study.

Katayoun Rezaei, Sandra Abou Kassm, María Sofía Garcés-González, Marina Sánchez-Rico, Mark Olfson, Charles Ouazana-Vedrines, Valentin Scheer, Mahdi Fayad, Pierre Meneton, Frédéric Limosin and 2 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katayoun RezaeiDépartement de Psychiatrie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Corentin-Celton, Issy-les-Moulineaux, France.
Sandra Abou KassmDepartment of Psychiatry, Centre Hospitalier Guillaume Régnier, Rennes, France.
María Sofía Garcés-GonzálezDépartement de Psychiatrie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Corentin-Celton, Issy-les-Moulineaux, France. Department of Psychobiology & Behavioural Sciences Methods, Faculty of Psychology, Universidad Complutense de Madrid, Campus de Somosaguas, Pozuelo de Alarcon, Spain.
Marina Sánchez-RicoDépartement de Psychiatrie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Corentin-Celton, Issy-les-Moulineaux, France. Department of Psychobiology & Behavioural Sciences Methods, Faculty of Psychology, Universidad Complutense de Madrid, Campus de Somosaguas, Pozuelo de Alarcon, Spain.
Mark OlfsonDepartment of Psychiatry, Columbia University Medical Center/New York State Psychiatric Institute, New York, NY, USA.
Charles Ouazana-VedrinesUnité de Formation et de Recherche de Médecine, Facultéde Santé, Université Paris Cité, Paris, France. Service de Psychiatrie de l'Adulte, AP-HP, Hôpital Hôtel- Dieu, Paris, France. L'Institut National de la Santéet de la Recherche Médicale (INSERM), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (INRAE), Center for Research in Epidemiology and Statistics, Paris, France.
Valentin ScheerDépartement de Psychiatrie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Corentin-Celton, Issy-les-Moulineaux, France. Unitéde Formation et de Recherche de Médecine, Facultéde Santé, Université Paris Cité, Paris, France. Inserm Unité Mixte de Recherche (UMR) S1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Paris, France.
Mahdi FayadDépartement de Psychiatrie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Corentin-Celton, Issy-les-Moulineaux, France.
Pierre MenetonUMR 1142, INSERM, Université Paris 13, Sorbonne Université, Paris, France.
Frédéric LimosinDépartement de Psychiatrie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Corentin-Celton, Issy-les-Moulineaux, France. Unitéde Formation et de Recherche de Médecine, Facultéde Santé, Université Paris Cité, Paris, France. Inserm Unité Mixte de Recherche (UMR) S1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Paris, France.
Nicolas HoertelDépartement de Psychiatrie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Corentin-Celton, Issy-les-Moulineaux, France. Unitéde Formation et de Recherche de Médecine, Facultéde Santé, Université Paris Cité, Paris, France. Inserm Unité Mixte de Recherche (UMR) S1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Paris, France.
CSA Study Group

Funding

French Ministry of Health and Social Affairs PHRC 2008-N11-01French Psychiatric Congress
6 · The paper itself

Abstract

objectiveThe large body of literature examining the association between parenthood and mortality in the general population contrasts with a lack of such studies on older adults with schizophrenia. Identifying potential protective factors of premature death in this population is important to help guide prevention measures. Here, we examined whether all-cause and cause-specific mortality rates significantly differ between older parents and non-parents with schizophrenia during a 5-year follow-up.

methodsWe used data from a 5-year prospective multicenter sample of older adults with an ICD-10 diagnosis of schizophrenia (aged 55 years or more) recruited in France. We performed a forward stepwise logistic regression to examine the association between parenthood and all-cause mortality, including only independent variables that best explain outcome.

resultsOf the 323 older adults with schizophrenia, 133 (41.2%) were parents (mean age = 67.0, SD = 6.1) and 190 were not (mean age = 67.2, SD = 6.6). Following adjustments, parenthood was significantly associated with lower all-cause mortality compared to patients without children (21.1% [n=28] vs. 35.8% [n=68]; AOR = 0.50; 95%CI 0.27-0.94; p = 0.032); the association involved no significant sex differences.

conclusionParenthood could be a protective factor against mortality among older patients with schizophrenia who live in France. Further research is needed to understand the specific mechanisms underlying this association.

Indexed as

ParentsSchizophreniaAgedCause of DeathFemaleFranceHumansMaleMiddle AgedProspective StudiesRisk FactorsSocioeconomic FactorsadultschildrenmortalityParenthoodschizophrenia

Identifiers

PMID39331827
PMCPMC12681355

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.