Evidence map›Paper›PMID 39331790›Full record

ArticleACS infectious diseases2024

8-Hydroxyquinoline Series Exerts Bactericidal Activity against

Amala Bhagwat, Arielle Butts, Eric Greve, Yan Cheung, Eduard Melief, James Gomez, Deborah T Hung, Tanya Parish

Abstract read
In one paragraph

Article in ACS infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Nitroxoline exerts potent anti-Antimicrobial agents and chemotherapy · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amala BhagwatCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington 98109, United States.
Arielle ButtsCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington 98109, United States.
Eric GreveCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington 98109, United States.
Yan CheungAgilent Technologies Inc., Wood Dale, Illinois 60191, United States.
Eduard MeliefInfectious Disease Research Institute, Seattle, Washington 98102, United States.
James GomezBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.
Deborah T HungBroad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States.ORCID 0000-0003-4262-0673
Tanya ParishCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington 98109, United States.ORCID 0000-0001-7507-0423

Funding

The role of Esx-3 in mediating drug resistanceR01AI129360 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI PARISH, TANYA · 2018 to 2022
$1.8M
NIAID NIH HHS R01 AI129360
6 · The paper itself

Abstract

New drugs and mechanisms of action targeting

Indexed as

Antitubercular AgentsCopperMycobacterium tuberculosisOxyquinolineReactive Oxygen SpeciesHumansMicrobial Sensitivity TestsAntitubercular AgentsCopperOxyquinolineReactive Oxygen Speciesantibacterialsantitubercularbactericidal activitydrug discoverymetal ion homeostasistuberculosis

Identifiers

PMID39331790
PMCPMC11474974

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.