ArticlePLoS medicine2024
Decreases in purchases of energy, sodium, sugar, and saturated fat 3 years after implementation of the Chilean food labeling and marketing law: An interrupted time series analysis.
Article in PLoS medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ultra-processed food consumption and risk of multiple chronic diseases among 8,819,894 adults from 51 prospective cohorts: a dose-response meta-analysis.Family medicine and community health · 2026Pooled it
- Designing Social Media Health Warnings for Teenagers and Young Adults: A Randomized Clinical Trial.JAMA health forum · 2026Trial
- Nutrition Info and Other Front-of-Package Labels and Simulated Food and Beverage Purchases: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Prevalence of overweight and obesity and the burden of high body-mass index in Latin America: a systematic analysis for the Global Burden of Disease Study 2023.Lancet regional health. Americas · 2026Article
- Trends of Obesity in Early Adulthood and Later Adulthood Across 196 Countries and Territories, 1990-2022.Obesity (Silver Spring, Md.) · 2026Article
- Steatotic liver disease in Latin America: current views and perspectives.Nature reviews. Gastroenterology & hepatology · 2026Review
- Trends in the Prevalence of Foods High in Saturated Fats, Sodium, and Added Sugars among U.S. adults, NHANES 2007-2018.Journal of the Academy of Nutrition and Dietetics · 2026Article
- The Gut-brain-adipose Axis in Ultra-processed Food and Obesity: A Mechanistic Synthesis and Its Implications for Food Classification.Current obesity reports · 2026Review
- Integrating Policies that Enable Minimally Processed Foods with Policies that Restrict Ultra-Processed Foods for Obesity and Noncommunicable Disease Prevention.Current obesity reports · 2026Review
- Predicted Excess Cardiovascular Age and a Reverse Socioeconomic Gradient in a Middle-Income Latin American Country: A Population-Based Analysis of 163,889 Peruvians.Journal of cardiovascular development and disease · 2026Article
- Adoption and Acceptability of a Fruit and Vegetable Subsidy in Low-Income Households in Urban Chile: The Bolsillo Saludable Pilot Feasibility Study.Current developments in nutrition · 2026Article
- Eating Behavior and Eating Habits: From Infancy to Adolescence.Nutrients · 2026Review
- Sugar reduction in complex food systems: linking metabolic mechanisms, matrix engineering, and safety evaluation.NPJ science of food · 2026Review
- Product Reformulation in Response to the 2016 FDA Updated Nutrition Facts Label.JAMA health forum · 2026Article
- Association between unhealthy food consumption and mental health outcomes in children and adolescents: an umbrella review.Child and adolescent psychiatry and mental health · 2026Review
- Alignment with front-of-package labeling policy and risk of hospitalization: evidence from Canadian National Nutrition Survey linked to routinely collected health administrative databases.The American journal of clinical nutrition · 2026Article
- Color and shape matter: how visual design features of front-of-package warning labels influence attractiveness perception, healthfulness perception and purchase intention.Eating and weight disorders : EWD · 2026Article
- Which front-of-pack nutritional label (FOPNL) is most effective in promoting healthier dietary choices? An experimental study in Indonesia.BMJ public health · 2026Article
- Systematic review of impact of mandatory front-of-package nutrition labeling on behavioral and cognitive outcomes and inequalities.Revista panamericana de salud publica = Pan American journal of public health · 2026Review
- Translating nutrition science into national policy: comparative assessment of the 2025-2030 U. S. Dietary Guidelines and the Italian Mediterranean-based guidelines.Frontiers in nutrition · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundIn 2016, Chile implemented a multiphase set of policies that mandated warning labels, restricted food marketing to children, and banned school sales of foods and beverages high in nutrients of concern ("high-in" foods). Chile's law, particularly the warning label component, set the precedent for a rapid global proliferation of similar policies. While our initial evaluation showed policy-linked decreases in purchases of high-in, a longer-term evaluation is needed, particularly as later phases of Chile's law included stricter nutrient thresholds and introduced a daytime ban on advertising of high-in foods for all audiences. The objective is to evaluate changes in purchases of energy, sugar, sodium, and saturated fat purchased after Phase 2 implementation of the Chilean policies. METHODS AND
findingsThis interrupted time series study used longitudinal data on monthly food and beverage purchases from 2,844 Chilean households (138,391 household-months) from July 1, 2013 until June 25, 2019. Nutrition facts panel data from food and beverage packages were linked at the product level and reviewed by nutritionists. Products were considered "high-in" if they contained added sugar, sodium, or saturated fat and exceeded nutrient or calorie thresholds. Using correlated random-effects models and an interrupted time series design, we estimated the nutrient content of food and beverage purchases associated with Phase 1 and Phase 2 compared to a counterfactual scenario based on trends during a 36-month pre-policy timeframe. Compared to the counterfactual, we observed significant decreases in high-in purchases of foods and beverages during Phase 2, including a relative 36.8% reduction in sugar (-30.4 calories/capita/day, 95% CI -34.5, -26.3), a 23.0% relative reduction in energy (-51.6 calories/capita/day, 95% CI -60.7, -42.6), a 21.9% relative reduction in sodium (-85.8 mg/capita/day, 95% CI -105.0, -66.7), and a 15.7% relative reduction in saturated fat (-6.4 calories/capita/day, 95% CI -8.4, -4.3), while purchases of not-high-in foods and drinks increased. Reductions in sugar and energy purchases were driven by beverage purchases, whereas reductions in sodium and saturated fat were driven by foods. Compared to the counterfactual, changes in both high-in purchases and not high-in purchases observed in Phase 2 tended to be larger than changes observed in Phase 1. The pattern of changes in purchases was similar for households of lower versus higher socioeconomic status. A limitation of this study is that some results were sensitive to the use of shorter pre-policy time frames.
conclusionsCompared to a counterfactual based on a 36-month pre-policy timeframe, Chilean policies on food labeling, marketing, and school food sales led to declines in nutrients of concern during Phase 2 of implementation, particularly from foods and drinks high in nutrients of concern. These declines were sustained or even increased over phases of policy implementation.
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