Evidence map›Paper›PMID 39331520›Full record

ArticleeLife2024

Local volume concentration, packing domains, and scaling properties of chromatin.

Marcelo A Carignano, Martin Kroeger, Luay M Almassalha, Vasundhara Agrawal, Wing Shun Li, Emily M Pujadas-Liwag, Rikkert J Nap, Vadim Backman, Igal Szleifer

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Marcelo A Carignano *Department of Biomedical Engineering, Northwestern University, Evanston, United States.ORCID https://orcid.org/0000-0001-8345-7724
Martin Kroeger *Magnetism and Interface Physics & Computational Polymer Physics, Department of Materials, ETH Zurich, Zurich, Switzerland.
Luay M Almassalha *Department of Gastroenterology and Hepatology, Northwestern Memorial Hospital, Evanston, United States.ORCID https://orcid.org/0000-0001-9355-7681
Vasundhara AgrawalDepartment of Biomedical Engineering, Northwestern University, Evanston, United States.ORCID https://orcid.org/0000-0003-0913-9298
Wing Shun LiApplied Physics Program, Northwestern University, Chicago, United States.
Emily M Pujadas-LiwagDepartment of Biomedical Engineering, Northwestern University, Evanston, United States.
Rikkert J NapDepartment of Biomedical Engineering, Northwestern University, Evanston, United States.
Vadim BackmanDepartment of Biomedical Engineering, Northwestern University, Evanston, United States.ORCID https://orcid.org/0000-0003-1981-1818
Igal SzleiferDepartment of Biomedical Engineering, Northwestern University, Evanston, United States.ORCID https://orcid.org/0000-0002-8708-0335

Funding

Technology Development UnitU54CA268084 · NCI · NORTHWESTERN UNIVERSITY · PI Vadim Backman, Daniela E Matei · 2022 to 2026
$10.0M
Studying E-cadherin dynamics during extravasation and metastatic colonizationU54CA261694 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ROGER D KAMM, Vivek Shenoy · 2021 to 2026
$9.1M
Translating buccal nanocytology for lung cancer screening into clinical practiceR01CA225002 · NCI · NORTHWESTERN UNIVERSITY · PI Vadim Backman, HARIHARAN SUBRAMANIAN · 2018 to 2026
$5.0M
Northwestern University Allergy Immunology Research Program (NUAIR)T32AI083216 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Stephanie Caroline Eisenbarth, ADAM WILLIAMS · 2010 to 2026
$4.1M
Microvasculature in Colon Field Carcinogenesis: Clinical-Biological ImplicationsR01CA224911 · NCI · BOSTON MEDICAL CENTER · PI BACKMAN, VADIM, ROY, HEMANT K. · 2018 to 2022
$3.3M
Reducing Cancer Transcriptional Heterogeneity through Regulation of Chromatin StructureR01CA228272 · NCI · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM, ROY, HEMANT K. · 2018 to 2022
$3.2M
Physical Genomics and Engineering Training ProgramT32GM142604 · NIGMS · NORTHWESTERN UNIVERSITY · PI BACKMAN, VADIM · 2021 to 2025
$1.9M
National Institute of Allergy and Infectious Diseases T32AI083216National Science Foundation EFMA-1830961NCI NIH HHS R01 CA224911NCI NIH HHS R01CA224911NCI NIH HHS R01 CA225002NCI NIH HHS R01CA225002NCI NIH HHS R01 CA228272NCI NIH HHS R01CA228272NCI NIH HHS U54 CA261694NCI NIH HHS U54CA261694NCI NIH HHS U54 CA268084NCI NIH HHS U54CA268084NIAID NIH HHS T32 AI083216NIGMS NIH HHS T32 GM142604NIGMS NIH HHS T32GM142604
6 · The paper itself

Abstract

We propose the Self Returning Excluded Volume (SR-EV) model for the structure of chromatin based on stochastic rules and physical interactions. The SR-EV

Indexed as

ChromatinHumansNucleosomesSingle-Cell AnalysisChromatinNucleosomeschromatinnonephysics of living systemsSR-EVtheory

Identifiers

PMID39331520
PMCPMC11434620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.