Evidence map›Paper›PMID 39331308›Full record

ArticleJournal of ophthalmic inflammation and infection2024

Occlusive retinal vasculitis associated with intravitreal Faricimab injections.

Felix F Reichel, Peter Kiraly, Roopa Vemala, Stella Hornby, Samantha R De Silva, M Dominik Fischer

Abstract read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Felix F ReichelCentre for Ophthalmology, University Eye Hospital, University Hospital Tübingen, Tübingen, Germany. felix.reichel@ouh.nhs.uk.
Peter KiralyCentre for Ophthalmology, University Eye Hospital, University Hospital Tübingen, Tübingen, Germany.
Roopa VemalaCentre for Ophthalmology, University Eye Hospital, University Hospital Tübingen, Tübingen, Germany.
Stella HornbyCentre for Ophthalmology, University Eye Hospital, University Hospital Tübingen, Tübingen, Germany.
Samantha R De SilvaCentre for Ophthalmology, University Eye Hospital, University Hospital Tübingen, Tübingen, Germany.
M Dominik FischerCentre for Ophthalmology, University Eye Hospital, University Hospital Tübingen, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe describe a case of occlusive vasculitis associated with intravitreal Faricimab (Vabysmo) injections.

methodsA retrospective case report.

resultsA 52-year old man treated with monthly Faricimab injections for diabetic macula oedema presented with sudden reduced vision, new retinal hemorrhages, significant retinal vascular occlusions and ischemia. After screening for differential diagnoses was unremarkable, the patient was treated with oral and intravitreal steroid therapy under which the occlusive vasculitis was stabilized.

conclusionOcclusive vasculitis, though rare, is a potential complication of Faricimab therapy. Comprehensive reporting and large-scale analyses are essential to better understand and manage this adverse event.

Indexed as

Diabetic retinopathyFaricimabOcclusive vasculitisVabysmo

Identifiers

PMID39331308
PMCPMC11436497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.