Evidence map›Paper›PMID 39330908›Full record

ReviewTropical medicine and infectious disease2024

Evaluation of Chemokines MIG and IP-10 as Immunological Biomarkers of Human Visceral Leishmaniasis: A Systematic Review.

Bruna Eduarda Freitas Monteiro, Elis Dionísio da Silva, Walter Lins Barbosa Júnior, Amanda Virginia Batista Vieira, Roberta Dos Santos Souza, Maria Karollyne Dos Santos Paiva, Pablo Cantalice Santos Farias, Diego Lins Guedes, Gilberto Silva Nunes Bezerra, Zulma Maria de Medeiros

Abstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bruna Eduarda Freitas MonteiroGraduate Program in Health Biosciences and Biotechnology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation (Fiocruz), Recife 50670-420, PE, Brazil.ORCID 0000-0002-9999-7036
Elis Dionísio da SilvaHealth and Biotechnology Institute, Federal University of Amazonas, Coari 69460-000, AM, Brazil.
Walter Lins Barbosa JúniorDepartment of Parasitology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation (Fiocruz), Recife 50670-420, PE, Brazil.ORCID 0000-0002-8301-6600
Amanda Virginia Batista VieiraDepartment of Parasitology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation (Fiocruz), Recife 50670-420, PE, Brazil.
Roberta Dos Santos SouzaDepartment of Parasitology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation (Fiocruz), Recife 50670-420, PE, Brazil.
Maria Karollyne Dos Santos PaivaAggeu Magalhães Institute, Oswaldo Cruz Foundation (Fiocruz), Recife 50670-420, PE, Brazil.
Pablo Cantalice Santos FariasDepartment of Genetics, Federal University of Pernambuco, Recife 50670-420, PE, Brazil.ORCID 0000-0001-8734-3468
Diego Lins GuedesFaculty of Medical Sciences, University of Pernambuco, Recife 50100-130, PE, Brazil.ORCID 0000-0002-1907-315X
Gilberto Silva Nunes BezerraDepartment of Nursing & Healthcare, Technological University of the Shannon: Midlands Midwest, N37 HD68 Athlone, Ireland.ORCID 0000-0001-7434-3223
Zulma Maria de MedeirosGraduate Program in Health Biosciences and Biotechnology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation (Fiocruz), Recife 50670-420, PE, Brazil.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco IBPG-2281-2.10/22
6 · The paper itself

Abstract

Visceral leishmaniasis (VL) is a neglected tropical disease that is potentially fatal when untreated. Current diagnostic methods have limitations that contribute to ongoing transmission and poor prognosis. Thus, new tests are needed to provide quick, accurate diagnoses and evaluate clinical progression and treatment efficacy. The monokine induced by interferon-gamma (MIG) and interferon-gamma-inducible protein 10 (IP-10) has been associated with the host susceptibility to VL with potential diagnostic and prognostic purposes. We performed a systematic review using four search databases (Scopus, PubMed, Web of Science, and MEDLINE) to identify studies assessing MIG and IP-10 as potential biomarkers in patients with VL across various clinical conditions. A total of 13 studies were potentially eligible and included in this review. The articles, in general, reveal that the chemokines MIG and IP-10 are elevated in response to infection by

Indexed as

biomarkerchemokinesIP-10MIGsystematic reviewvisceral leishmaniasis

Identifiers

PMID39330908
PMCPMC11435945

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.