Evidence map›Paper›PMID 39330895›Full record

ArticleTropical medicine and infectious disease2024

Efficacy of Adjunct Hemoperfusion Compared to Standard Medical Therapy on 28-Day Mortality in Leptospirosis Patients with Renal Failure and Shock: A Single-Center Randomized Controlled Trial.

Danice Romagne Leano, Romina Danguilan, Mel-Hatra Arakama, Vince Apelin, Paolo Pinkerton Alamillo, Eric Chua

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danice Romagne LeanoDepartment of Adult Nephrology, National Kidney and Transplant Institute, Quezon City 1101, Philippines.
Romina DanguilanDepartment of Adult Nephrology, National Kidney and Transplant Institute, Quezon City 1101, Philippines.
Mel-Hatra ArakamaDepartment of Adult Nephrology, National Kidney and Transplant Institute, Quezon City 1101, Philippines.ORCID 0000-0002-0379-3021
Vince ApelinDepartment of Adult Nephrology, National Kidney and Transplant Institute, Quezon City 1101, Philippines.
Paolo Pinkerton AlamilloDepartment of Adult Nephrology, National Kidney and Transplant Institute, Quezon City 1101, Philippines.
Eric ChuaDepartment of Adult Nephrology, National Kidney and Transplant Institute, Quezon City 1101, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemoperfusion is a novel adjunct therapy that targets the dysregulated inflammatory events in severe sepsis. Previous studies have reported conflicting results on its efficacy and safety. This study was designed to assess the efficacy and safety of hemoperfusion among leptospirosis patients in septic shock and renal failure in terms of improvement in 28-day mortality, SOFA score, level of inflammatory markers, hemodynamics, and renal and pulmonary function. A total of 37 severe leptospirosis patients were enrolled and randomized into either standard medical therapy (SMT) alone,

Indexed as

cytokine stormhemoperfusionleptospirosismortalityseptic shock

Identifiers

PMID39330895
PMCPMC11435429

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.