ArticleTropical medicine and infectious disease2024
Factors Contributing to In-Hospital Mortality in Dengue: Insights from National Surveillance Data in Mexico (2020-2024).
Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association of dengue severity with the serotype of infection: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Epidemic Years Increase Hospitalization but Not Mortality Among Laboratory-Confirmed Dengue Cases in Mexico: A Nationwide Surveillance Study, 2020-2025.Microorganisms · 2026Article
- Assessing the burden of diabetes mellitus in dengue patients: A systematic review and meta-analysis.New microbes and new infections · 2026Article
- Beyond Borders-Tackling Neglected Tropical Viral Diseases.Tropical medicine and infectious disease · 2026Article
- Adverse dengue outcomes in patients with chronic kidney disease: A population-based analysis of 5.8 million individuals from Brazil.PLoS neglected tropical diseases · 2026Article
- Article
- Noncommunicable diseases associated with bleeding disorders, hospitalization, and mortality in patients with dengue in Mexico: A national analysis of confirmed cases in 2024.PLoS neglected tropical diseases · 2025Article
- Impact of migratory flows and socio-environmental factors on dengue epidemiology in Oaxaca, Mexico.Frontiers in sociology · 2025Review
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
This study aimed to identify the factors associated with all-cause in-hospital mortality in laboratory-confirmed dengue cases from 2020 to mid-2024. A nationwide retrospective cohort study was conducted in Mexico and data from 18,436 participants were analyzed. Risk ratios (RRs) and 95% confidence intervals (CIs), estimated using generalized linear regression models, were used to evaluate the factors associated with all-cause in-hospital mortality risk. The overall case-fatality rate was 17.5 per 1000. In the multiple model, compared to dengue virus (DENV) 1 infections, DENV-2 (RR = 1.81, 95% CI 1.15-2.86) and DENV-3 (RR = 1.87, 95% CI 1.19-2.92) were associated with increased mortality risk. Patient characteristics, such as increasing age (RR = 1.02, 95% CI 1.01-1.03), type 2 diabetes mellitus (RR = 2.07, 95% CI 1.45-2.96), and chronic kidney disease (RR = 3.35, 95% CI 2.03-5.51), were also associated with an increased risk of a fatal outcome. We documented the influence of both the virus and individual susceptibility on mortality risk, underscoring the need for a comprehensive public health strategy for dengue.
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