Evidence map›Paper›PMID 39330881›Full record

ArticleTropical medicine and infectious disease2024

Trypanocide Use and Molecular Characterization of Trypanosomes Resistant to Diminazene Aceturate in Cattle in Northern Côte D'Ivoire.

Jean-Yves Ekra, Eliakunda Michael Mafie, Henri Sonan, Michael Kanh, Biégo Guillaume Gragnon, Edouard K N'Goran, Jagan Srinivasan

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jean-Yves EkraDepartment of Veterinary Microbiology Parasitology and Biotechnology, Sokoine University of Agriculture, Morogoro 67125, Tanzania.ORCID 0000-0002-6617-3751
Eliakunda Michael MafieDepartment of Veterinary Microbiology Parasitology and Biotechnology, Sokoine University of Agriculture, Morogoro 67125, Tanzania.ORCID 0000-0002-1416-292X
Henri SonanUnité de Formation et de Recherche (UFR) des Sciences Biologiques, Département de Biochimie-Génétique, Université Peleforo Gon Coulibaly, Korhogo BP1328, Côte d'Ivoire.
Michael KanhUnité de Formation et de Recherche (UFR) des Sciences Biologiques, Département de Biochimie-Génétique, Université Peleforo Gon Coulibaly, Korhogo BP1328, Côte d'Ivoire.
Biégo Guillaume GragnonLaboratoire National d'Appui au Développement Agricole (LANADA), Korhogo BP1328, Côte d'Ivoire.
Edouard K N'GoranUnité de Formation et de Recherche (UFR) des Sciences Biologiques, Département de Biochimie-Génétique, Université Peleforo Gon Coulibaly, Korhogo BP1328, Côte d'Ivoire.
Jagan SrinivasanDepartment of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA 01609, USA.ORCID 0000-0001-5449-7938

Funding

Partnership for Skills in Applied Sciences, Engineering, and Technology (PASET) through the Regional Scholarship and Innovation Fund (RSIF) Cohort 2
6 · The paper itself

Abstract

The resistance of trypanosomes to the doses of trypanocide administered by farmers to their animals acts as a real brake on efforts to control to combat African trypanosomiasis. Thus, in-depth knowledge of the use of these different molecules and their resistance profiles will be necessary to establish an integrated strategy to combat African trypanosomiasis. To achieve these objectives, a participatory survey among farmers and a resistance diagnosis of trypanosome strains identified in three regions of northern Côte d'Ivoire (Bagoué, Poro and Tchologo) was carried out using the PCR-RFLP technique, followed by sequencing of genes of interest. This study made it possible to identify three molecules that are commonly used by 85% (63/74) of farmers. In descending order of use, we identified Isometamidium chloride (43%), Diminazene aceturate (28%) and Homidium bromide (14%). Three species of trypanosomes,

Indexed as

cattleCôte d’Ivoireresistancetrypanocidetrypanosome

Identifiers

PMID39330881
PMCPMC11435713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.