ArticleToxins2024
The Role of the N-Terminal Domain of Thrombomodulin and the Potential of Recombinant Human Thrombomodulin as a Therapeutic Intervention for Shiga Toxin-Induced Hemolytic-Uremic Syndrome.
Sarah Kröller, Jana Schober, Nadine Krieg, Sophie Dennhardt, Wiebke Pirschel, Michael Kiehntopf, Edward M Conway, Sina M Coldewey
Abstract read
In one paragraphArticle in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Sarah KröllerDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07747 Jena, Germany.
Jana SchoberDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07747 Jena, Germany.
Nadine KriegDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07747 Jena, Germany.
Sophie DennhardtDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07747 Jena, Germany.
Wiebke PirschelDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07747 Jena, Germany.
Michael KiehntopfDepartment of Clinical Chemistry and Laboratory Medicine, Jena University Hospital, 07747 Jena, Germany.
Edward M ConwayCentre for Blood Research, Life Sciences Institute, Department of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0003-0081-0305 Sina M ColdeweyDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-7130-0006 Funding
Canadian Institutes for Health Research CanVECTORFederal Ministry of Education and Research 03Z22JN12Federal Ministry of Education and Research, ICROVID 03COV07German Research Foundation, Collaborative Research Centre PolyTarget 1278-2021, subproject A02 316213987German Research Foundation Research Unit FOR1738 CO912/2-1
6 · The paper itselfAbstract
Hemolytic-uremic syndrome (HUS) is a rare complication of an infection with Shiga toxin (Stx)-producing
Indexed as
Hemolytic-Uremic SyndromeRecombinant ProteinsThrombomodulinAnimalsDisease Models, AnimalHumansMiceProtein DomainsShiga ToxinRecombinant ProteinsShiga ToxinTHBD protein, humanThrombomodulinexperimental HUS modelhemolytic-uremic syndromekidney injuryrecombinant human thrombomodulinShiga toxinthrombomodulin
Identifiers
PMID39330867
PMCPMC11435709
What OpenQuestion holds
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