Evidence map›Paper›PMID 39330862›Full record

ArticleToxins2024

Enzymatic Hydrolysis of Resorcylic Acid Lactones by an

Shawn J Hoogstra, Kyle N Hendricks, David R McMullin, Justin B Renaud, Juhi Bora, Mark W Sumarah, Christopher P Garnham

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shawn J HoogstraLondon Research and Development Center, Agriculture and Agri-Food Canada, London, ON N5V 4T3, Canada.ORCID 0000-0003-2533-9310
Kyle N HendricksLondon Research and Development Center, Agriculture and Agri-Food Canada, London, ON N5V 4T3, Canada.ORCID 0000-0003-2303-2438
David R McMullinDepartment of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.ORCID 0000-0001-9808-924X
Justin B RenaudLondon Research and Development Center, Agriculture and Agri-Food Canada, London, ON N5V 4T3, Canada.
Juhi BoraLondon Research and Development Center, Agriculture and Agri-Food Canada, London, ON N5V 4T3, Canada.
Mark W SumarahLondon Research and Development Center, Agriculture and Agri-Food Canada, London, ON N5V 4T3, Canada.ORCID 0000-0003-0977-1656
Christopher P GarnhamLondon Research and Development Center, Agriculture and Agri-Food Canada, London, ON N5V 4T3, Canada.

Funding

Agriculture & Agri-Food Canada CAP-ASP-110, SCAP-ASP-026, CRDA J-002398
6 · The paper itself

Abstract

Zearalenone and radicicol are resorcylic acid lactones produced by numerous plant pathogenic fungi. Zearalenone is a non-steroidal estrogen mimic that can cause serious reproductive issues in livestock that consume contaminated feed. Radicicol is a potent inhibitor of the molecular chaperone Hsp90, which, in plants, has an important role in coordinating the host's immune response during infection. Here, we describe the identification and characterization of a soil-borne strain of the Gram-positive bacterium

Indexed as

LactonesZearalenoneHydrolasesHydrolysisMacrolidesHydrolasesLactonesMacrolidesmonordenZearalenoneAeromicrobium sp.biotransformationheat shock protein 90 (Hsp90)HZENradicicolresorcylic acid lactonezearalenoneα/β-hydrolase

Identifiers

PMID39330862
PMCPMC11435890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.