Evidence map›Paper›PMID 39330590›Full record

ArticleToxics2024

Recreational Drug Overdose-Clinical Value of Toxicological Analysis.

Tobias Zellner, Florian Eyer, Christian Rabe, Stefanie Geith, Bettina Haberl, Sabrina Schmoll

Abstract read
In one paragraph

Article in Toxics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tobias ZellnerDivision of Clinical Toxicology, Poison Centre Munich, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0001-5073-8685
Florian EyerDivision of Clinical Toxicology, Poison Centre Munich, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0002-4753-2747
Christian RabeDivision of Clinical Toxicology, Poison Centre Munich, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.
Stefanie GeithDivision of Clinical Toxicology, Poison Centre Munich, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.ORCID 0000-0002-2726-2823
Bettina HaberlDivision of Clinical Toxicology, Poison Centre Munich, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.
Sabrina SchmollDivision of Clinical Toxicology, Poison Centre Munich, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToxicological analysis of patients with acute recreational drug poisoning can improve our understanding of substance use patterns, clinical symptoms, and improve treatment. Patient history alone may be incomplete or misleading. The objective was to assess the differences in patient history and analytical results, to describe the clinical characteristics, implications and hospital management, and to describe the drug use pattern over time.

methodsA retrospective study including all patients admitted to our toxicology unit with recreational drug toxicity and analytical testing from October 2014 to December 2022.

results872 patients were included. Patient history revealed a median of one ingested substance class: opiates/opioids, benzodiazepines/Z-drugs, and Pregabalin were predominant. Urine analysis revealed a median of three ingested substance classes (

conclusionsPatient history is inaccurate, and patients frequently underreport ingested drugs. Opiates and opioids are still the main cause of morbidity and mortality. Pregabalin is increasingly abused. NPS legislation effectively decreased cathinone/phenethylamine and synthetic cannabinoid receptor agonist overdoses.

Indexed as

benzodiazepine/Z-drugclinical relevanceNPSopiate/opioidPregabalinrecreational drug overdosetoxicological analysis

Identifiers

PMID39330590
PMCPMC11436079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.