Evidence map›Paper›PMID 39330438›Full record

ArticleJournal of imaging2024

Decoding Breast Cancer: Using Radiomics to Non-Invasively Unveil Molecular Subtypes Directly from Mammographic Images.

Manon A G Bakker, Maria de Lurdes Ovalho, Nuno Matela, Ana M Mota

Abstract read
In one paragraph

Article in Journal of imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manon A G BakkerFaculty of Science and Engineering, University of Groningen, 9700 AS Groningen, The Netherlands.ORCID 0009-0008-1580-0381
Maria de Lurdes OvalhoDepartamento de Radiologia, Hospital da Luz Lisboa, Luz Saúde, 1500-650 Lisboa, Portugal.
Nuno MatelaInstituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências, Universidade de Lisboa, 1649-004 Lisbon, Portugal.ORCID 0000-0002-8048-7896
Ana M MotaInstituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências, Universidade de Lisboa, 1649-004 Lisbon, Portugal.ORCID 0000-0002-1931-294X

Funding

Fundação para a Ciência e Tecnologia-Portugal FCT-IBEB 285 Strategic Project UIDB/00645/2020
6 · The paper itself

Abstract

Breast cancer is the most commonly diagnosed cancer worldwide. The therapy used and its success depend highly on the histology of the tumor. This study aimed to explore the potential of predicting the molecular subtype of breast cancer using radiomic features extracted from screening digital mammography (DM) images. A retrospective study was performed using the OPTIMAM Mammography Image Database (OMI-DB). Four binary classification tasks were performed: luminal A vs. non-luminal A, luminal B vs. non-luminal B, TNBC vs. non-TNBC, and HER2 vs. non-HER2. Feature selection was carried out by Pearson correlation and LASSO. The support vector machine (SVM) and naive Bayes (NB) ML classifiers were used, and their performance was evaluated with the accuracy and the area under the receiver operating characteristic curve (AUC). A total of 186 patients were included in the study: 58 luminal A, 35 luminal B, 52 TNBC, and 41 HER2. The SVM classifier resulted in AUCs during testing of 0.855 for luminal A, 0.812 for luminal B, 0.789 for TNBC, and 0.755 for HER2, respectively. The NB classifier showed AUCs during testing of 0.714 for luminal A, 0.746 for luminal B, 0.593 for TNBC, and 0.714 for HER2. The SVM classifier outperformed NB with statistical significance for luminal A (

Indexed as

breast cancermachine learningmammographymolecular subtypesnaive Bayesradiomicssupport vector machine

Identifiers

PMID39330438
PMCPMC11432960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.