Evidence map›Paper›PMID 39330318›Full record

ReviewJournal of cardiovascular development and disease2024

Spinal Cord Stimulation for Intractable Chronic Limb Ischemia: A Narrative Review.

Roberto Gazzeri, Tommaso Castrucci, Matteo Luigi Giuseppe Leoni, Marco Mercieri, Felice Occhigrossi

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roberto GazzeriInterventional and Surgical Pain Management Unit, San Giovanni-Addolorata Hospital, Via Amba Aradam 9, 00184 Rome, Italy.ORCID 0000-0003-1356-1846
Tommaso CastrucciVascular Surgery Unit, Sant'Eugenio Hospital, 00144 Rome, Italy.
Matteo Luigi Giuseppe LeoniDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, 29121 Rome, Italy.ORCID 0000-0001-5228-3733
Marco MercieriDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, 29121 Rome, Italy.ORCID 0000-0003-4321-6525
Felice OcchigrossiInterventional and Surgical Pain Management Unit, San Giovanni-Addolorata Hospital, Via Amba Aradam 9, 00184 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critical limb ischemia (CLI) is the most severe form of peripheral arterial disease, significantly impacting quality of life, morbidity and mortality. Common complications include severe limb pain, walking difficulties, ulcerations and limb amputations. For cases of CLI where surgical or endovascular reconstruction is not possible or fails, spinal cord stimulation (SCS) may be a treatment option. Currently, SCS is primarily prescribed as a symptomatic treatment for painful symptoms. It is used to treat intractable pain arising from various disorders, such as neuropathic pain secondary to persistent spinal pain syndrome (PSPS) and painful diabetic neuropathy. Data regarding the effect of SCS in treating CLI are varied, with the mechanism of action of vasodilatation in the peripheral microcirculatory system not yet fully understood. This review focuses on the surgical technique, new modalities of SCS, the mechanisms of action of SCS in vascular diseases and the parameters for selecting CLI patients, along with the clinical outcomes and complications. SCS is a safe and effective surgical option in selected patients with CLI, where surgical or endovascular revascularization is not feasible.

Indexed as

clinical outcomesintractable critical limb ischemia (ICLI)neuropathic painnew SCS modalitiesperipheral arterial disease (PAD)spinal cord stimulation (SCS)

Identifiers

PMID39330318
PMCPMC11431887

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.