Evidence map›Paper›PMID 39330291›Full record

ArticleMarine drugs2024

Altechromone A Ameliorates Inflammatory Bowel Disease by Inhibiting NF-κB and NLRP3 Pathways.

Lei Li, Jing Huang, Lixin Feng, Liyan Xu, Houwen Lin, Kechun Liu, Xiaobin Li, Rongchun Wang

Abstract read
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei LiBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0009-0003-4619-2319
Jing HuangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Lixin FengBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Liyan XuBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Houwen LinBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0000-0002-7097-0876
Kechun LiuBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Xiaobin LiBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0000-0002-3775-7694
Rongchun WangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.

Funding

National Natural Science Foundation of China U2006204Shandong Provincial Natural Science Foundation ZR2021ZD29 and ZR2022MH240Taishan Scholar Project from Shandong Province ts20190950Taishan Scholars Program TSQN202312233
6 · The paper itself

Abstract

Altechromone A, also known as 2,5-dimethyl-7-hydroxychromone, is a hydroxyketone containing one hydroxyl and one ketone group. In this study, we isolated Altechromone A from the marine-derived fungus

Indexed as

Anti-Inflammatory AgentsDisease Models, AnimalInflammatory Bowel DiseasesNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinZebrafishAnimalsPenicillium chrysogenumReactive Oxygen SpeciesSignal TransductionAnti-Inflammatory AgentsNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinReactive Oxygen SpeciesAltechromone Aanti-inflammatory activityinflammatory bowel diseaseNOD pathwayzebrafish

Identifiers

PMID39330291
PMCPMC11432983

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.