Evidence map›Paper›PMID 39330244›Full record

ArticleJournal of functional biomaterials2024

Impact of Calcium Lactate Pretreatment on Enamel Fluoride Uptake: A Comparative In Vitro Study of Different Fluoride Types and Concentrations.

Fjolla Kullashi Spahija, Ivana Sutej, Kresimir Basic, Kreshnik Spahija, Kristina Peros

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fjolla Kullashi SpahijaDepartment of Pharmacology, School of Dental Medicine, 10000 Zagreb, Croatia.ORCID 0009-0003-7370-0526
Ivana SutejDepartment of Pharmacology, School of Dental Medicine, 10000 Zagreb, Croatia.ORCID 0000-0001-7654-0079
Kresimir BasicDepartment of Pharmacology, School of Dental Medicine, 10000 Zagreb, Croatia.ORCID 0000-0002-9854-5708
Kreshnik SpahijaDental Policlinic Center, 30000 Peja, Kosovo.
Kristina PerosDepartment of Pharmacology, School of Dental Medicine, 10000 Zagreb, Croatia.ORCID 0000-0002-0797-9587

Funding

Ministry of Science, Education and Sports University of Zagreb, School of Dental Medicine 2022-2024
6 · The paper itself

Abstract

(1) Background: This study aimed to establish the effect of calcium lactate enamel pretreatment related to different fluoride types and concentrations on the enamel uptake of alkali-soluble fluorides. (2) Materials: In a blind and randomized in vitro study, a total of 60 teeth are used. The first 30 teeth were cut and randomly allocated into one of the following treatments: (A) calcium lactate pretreatment followed by three different fluoride solutions; (B) the "Fluoride only" group, with slabs treated with three different fluoride solutions; (C) the "Calcium only" group, with slabs treated with calcium lactate solution; (D) slabs treated with deionized water (negative control group). The next 30 teeth underwent all the above described group procedures but were treated with lower fluoride concentrations. Fluoride was extracted from enamel using 1 M KOH solution and analyzed using a fluoride ion-specific electrode. (3) Results: The findings revealed that slabs treated with NaF following calcium lactate pretreatment exhibited significantly greater enamel uptake of alkali-soluble fluoride compared to other substrates. This significant effect was not observed at lower fluoride concentrations. (4) Conclusion: The study demonstrates that pretreatment with calcium lactate followed by treatment with NaF at 226 ppm F significantly enhances the uptake of alkali-soluble fluoride in enamel compared to other fluoride types.

Indexed as

aminofluoridecalcium lactatemonofluorophosphatesodium fluoride

Identifiers

PMID39330244
PMCPMC11433163

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.