Evidence map›Paper›PMID 39330127›Full record

ReviewEntropy (Basel, Switzerland)2024

Is Seeing Believing? A Practitioner's Perspective on High-Dimensional Statistical Inference in Cancer Genomics Studies.

Kun Fan, Srijana Subedi, Gongshun Yang, Xi Lu, Jie Ren, Cen Wu

Abstract readReview
In one paragraph

Review in Entropy (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kun FanDepartment of Statistics, Kansas State University, Manhattan, KS 66506, USA.
Srijana SubediDepartment of Statistics, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-9262-5985
Gongshun YangDepartment of Statistics, Kansas State University, Manhattan, KS 66506, USA.
Xi LuDepartment of Pharmaceutical Health Outcomes and Policy, College of Pharmacy, University of Houston, Houston, TX 77204, USA.
Jie RenDepartment of Biostatistics and Health Data Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID 0000-0002-7823-6262
Cen WuDepartment of Statistics, Kansas State University, Manhattan, KS 66506, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Variable selection methods have been extensively developed for and applied to cancer genomics data to identify important omics features associated with complex disease traits, including cancer outcomes. However, the reliability and reproducibility of the findings are in question if valid inferential procedures are not available to quantify the uncertainty of the findings. In this article, we provide a gentle but systematic review of high-dimensional frequentist and Bayesian inferential tools under sparse models which can yield uncertainty quantification measures, including confidence (or Bayesian credible) intervals,

Indexed as

exact sparsityfrequentist and Bayesian variable selectionregularized variable selectionrobust Bayesian inferenceuncertainty quantification

Identifiers

PMID39330127
PMCPMC11430850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.