Evidence map›Paper›PMID 39329824›Full record

ReviewBiosensors2024

Microfluidic Gastrointestinal Cell Culture Technologies-Improvements in the Past Decade.

Adrian J T Teo, Siu-Kin Ng, Kaydeson Khoo, Sunny Hei Wong, King Ho Holden Li

Abstract readReview
In one paragraph

Review in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adrian J T TeoSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore.
Siu-Kin NgLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.
Kaydeson KhooSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore.
Sunny Hei WongLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.ORCID 0000-0002-3354-9310
King Ho Holden LiSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore.ORCID 0000-0001-6187-6434

Funding

Ministry of Education Academic Research Fund Tier 1 (RG37/22)Ministry of Health National Medical Research Council Clinician-Scientist Individual Research Grant CIRG23Jan-0004 MOH-001353Ministry of Health National Medical Research Council Open Fund-Large Collaborative Grant OFLCG22May-0009NTU Start Up Grant NTU Start Up GrantWang Lee Wah Memorial Fund Wang Lee Wah Memorial Fund
6 · The paper itself

Abstract

Gastrointestinal cell culture technology has evolved in the past decade with the integration of microfluidic technologies, bringing advantages with greater selectivity and cost effectiveness. Herein, these technologies are sorted into three categories, namely the cell-culture insert devices, conventional microfluidic devices, and 3D-printed microfluidic devices. Each category is discussed in brief with improvements also discussed here. Introduction of different companies and applications derived from each are also provided to encourage uptake. Subsequently, future perspectives of integrating microfluidics with trending topics like stool-derived in vitro communities and gut-immune-tumor axis investigations are discussed. Insights on modular microfluidics and its implications on gastrointestinal cell cultures are also discussed here. Future perspectives on point-of-care (POC) applications in relations to gastrointestinal microfluidic devices are also discussed here. In conclusion, this review presents an introduction of each microfluidic platform with an insight into the greater contribution of microfluidics in gastrointestinal cell cultures.

Indexed as

Cell Culture TechniquesGastrointestinal TractHumansLab-On-A-Chip DevicesMicrofluidic Analytical TechniquesMicrofluidicsPoint-of-Care Systemscell culturegastrointestinal tractgut-on-a-chipmicrofluidics

Identifiers

PMID39329824
PMCPMC11429516

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.