Evidence map›Paper›PMID 39329606›Full record

ArticleBioengineering (Basel, Switzerland)2024

Optimizing Production, Characterization, and In Vitro Behavior of Silymarin-Eudragit Electrosprayed Fiber for Anti-Inflammatory Effects: A Chemical Study.

Foram Madiyar, Liam Suskavcevic, Kaitlyn Daugherty, Alexis Weldon, Sahil Ghate, Takara O'Brien, Isabel Melendez, Karl Morgan, Sandra Boetcher, Lasya Namilae

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Foram MadiyarDepartment of Physical Science, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Liam SuskavcevicDepartment of Human Factors and Behavioral Neurobiology, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Kaitlyn DaughertyDepartment of Human Factors and Behavioral Neurobiology, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Alexis WeldonDepartment of Human Factors and Behavioral Neurobiology, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Sahil GhateDepartment of Electrical Engineering, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Takara O'BrienDepartment of Human Factors and Behavioral Neurobiology, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Isabel MelendezDepartment of Mechanical and Engineering Sciences, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Karl MorganDepartment of Mechanical and Engineering Sciences, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Sandra BoetcherDepartment of Mechanical and Engineering Sciences, Embry Riddle Aeronautical University, Daytona Beach, FL 32114, USA.
Lasya NamilaeSeminole High School, 2701 Ridgewood Ave, Sanford, FL 32773, USA.

Funding

Embry-Riddle Aeronautical University N/A
6 · The paper itself

Abstract

Inflammatory Bowel Disease (IBD) is a chronic condition that affects approximately 1.6 million Americans. While current polyphenols for treating IBD can be expensive and cause unwanted side effects, there is an opportunity regarding a new drug/polymer formulation using silymarin and an electrospray procedure. Silymarin is a naturally occurring polyphenolic flavonoid antioxidant that has shown promising results as a pharmacological agent due to its antioxidant and hepatoprotective characteristics. This study aims to produce a drug-polymer complex named the SILS100-Electrofiber complex, using an electrospray system. The vertical set-up of the electrospray system was optimized at a 1:10 of silymarin and Eudragit

Indexed as

drug–polymer complexelectrosprayinflammatory bowel diseasemicroencapsulationsilymarin

Identifiers

PMID39329606
PMCPMC11428713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.