ArticleBiomimetics (Basel, Switzerland)2024
Development and Evaluation of Fucoidan-Loaded Electrospun Polyvinyl Alcohol/Levan Nanofibers for Wound Dressing Applications.
Article in Biomimetics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Marine-Derived Polysaccharide Nanofibers for Wound Healing: Mechanistic Rationale, Biofabrication Strategies, and Translational Barriers.Pharmaceuticals (Basel, Switzerland) · 2026Review
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wound dressing is an ancient technique for promoting healing, and modern technology has led to the development of advanced dressings that enhance patient care. Nanofiber-based wound dressings are a medical innovation with enhanced properties, including improved adhesion, reduced infection rates, and increased tissue regeneration. This article focuses on electrospun nanofibrous wound dressing materials produced using the widely adopted method of electrospinning. This article explores several parameters that influence fiber size, including electrical conductivity, electric potential, collector distance, viscosity, flow rate, and surface tension. With Fucoidan (FUC) loading, an increase in the fiber diameter of the control group from 310 nm to 395 nm was observed. This research also examines the use of Halomonas Levan (HL), a polysaccharide, and polyvinyl alcohol (PVA) polymer as wound dressing materials to enhance the mechanical properties of the latter. The incorporation of various concentrations of FUC into PVA-HL electrospun nanofibers yielded diverse effects on tensile strength: an enhancement was observed in the PVA-HL-10FUC formulation, while reductions were noted in the PVA-HL-13FUC and PVA-HL-15FUC formulations. The WST1 assay demonstrated that none of the samples exhibited cytotoxicity up to 72 h, as cell viability increased over time. In conclusion, nanofibrous PVA-HL structures loaded with FUC, which promote tissue regeneration and prevent infection, could be considered a novel wound dressing material.
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Registered trials
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