Evidence map›Paper›PMID 39329363›Full record

ArticleeLife2024

Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action.

Ritwik Maity, Xuepei Zhang, Francesca Romana Liberati, Chiara Scribani Rossi, Francesca Cutruzzolá, Serena Rinaldo, Massimiliano Gaetani, José Antonio Aínsa, Javier Sancho

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Stability-based approaches in chemoproteomics.Expert reviews in molecular medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ritwik MaityBiocomputation and Complex Systems Physics Institute (BIFI)-Joint Unit GBsC-CSIC, University of Zaragoza, Zaragoza, Spain.ORCID https://orcid.org/0000-0003-4058-2888
Xuepei ZhangDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Francesca Romana LiberatiDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, Rome, Italy.
Chiara Scribani RossiDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0003-4855-4240
Francesca CutruzzoláDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, Rome, Italy.
Serena RinaldoDepartment of Biochemical Sciences "A. Rossi Fanelli", Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0003-0682-023X
Massimiliano GaetaniDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
José Antonio AínsaBiocomputation and Complex Systems Physics Institute (BIFI)-Joint Unit GBsC-CSIC, University of Zaragoza, Zaragoza, Spain.ORCID https://orcid.org/0000-0003-2076-844X
Javier SanchoBiocomputation and Complex Systems Physics Institute (BIFI)-Joint Unit GBsC-CSIC, University of Zaragoza, Zaragoza, Spain.ORCID https://orcid.org/0000-0002-2879-9200

Funding

Gobierno de Aragón E45_23RH2020 Marie Skłodowska-Curie Actions 10.3030/801586Horizon 2020 Framework Programme MOSBRI grant 101004806Horizon 2020 Framework Programme PID2019-107293GB-I00Joint Programming Initiative on Antimicrobial Resistance FLAV4AMRMinisterio de Ciencia, Innovación y Universidades PID2022-141068NB-I00
6 · The paper itself

Abstract

Antimicrobial resistance is responsible for an alarming number of deaths, estimated at 5 million per year. To combat priority pathogens, like

Indexed as

Anti-Bacterial AgentsHelicobacter pyloriProteomeSolubilityBacterial ProteinsMultiomicsProteomicsAnti-Bacterial AgentsBacterial ProteinsProteomeantimicrobial resistanceCagAcomputational biologyFtsZHelicobacter pyloriinfectious diseasemicrobiologymulti-omicssystems biologytarget deconvolution

Identifiers

PMID39329363
PMCPMC11434622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.