Evidence map›Paper›PMID 39329233›Full record

ArticleBiometrics2024

Discussion on "LEAP: the latent exchangeability prior for borrowing information from historical data" by Ethan M. Alt, Xiuya Chang, Xun Jiang, Qing Liu, May Mo, H. Amy Xia, and Joseph G. Ibrahim.

Shannon D Thomas, Alexander M Kaizer

Abstract read
In one paragraph

Article in Biometrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shannon D ThomasDepartment of Biostatistics and Informatives, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States.
Alexander M KaizerDepartment of Biostatistics and Informatives, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States.ORCID 0000-0003-2334-5514

Funding

Statistical Methods and Adaptive Trial Designs for Cardiovascular Outcomes with Information SharingK01HL151754 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI KAIZER, ALEXANDER MARK · 2021 to 2025
$742k
Cystic Fibrosis Foundation KAIZER23A0-KBNHLBI NIH HHS K01 HL151754NHLBI NIH HHS K01-HL151754
6 · The paper itself

Abstract

This discussion provides commentary on the paper by Ethan M. Alt, Xiuya Chang, Xun Jiang, Qing Liu, May Mo, H. Amy Xia, and Joseph G. Ibrahim entitled "LEAP: the latent exchangeability prior for borrowing information from historical data". The authors propose a novel method to bridge the incorporation of supplemental information into a study while also identifying potentially exchangeable subgroups to better facilitate information sharing. In this discussion, we highlight the potential relationship with other Bayesian model averaging approaches, such as multisource exchangeability modeling, and provide a brief numeric case study to illustrate how the concepts behind latent exchangeability prior may also improve the performance of existing methods. The results provided by Alt et al. are exciting, and we believe that the method represents a meaningful approach to more efficient information sharing.

Indexed as

Bayes TheoremBiometryData Interpretation, StatisticalHumansInformation DisseminationModels, StatisticalBayesian model averaginginformation sharingmultiple sourcesmultisource exchangeability models

Identifiers

PMID39329233
PMCPMC11427888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.