Evidence map›Paper›PMID 39328981›Full record

ArticleHealth science reports2024

Unlocking the medicinal arsenal of

Mohammad Abdullah Taher, Ripa Kundu, Aysha Akter Laboni, Suriya Akter Shompa, Md Moniruzzaman, Mohammad Mahmudul Hasan, Hasin Hasnat, Md Mehedi Hasan, Mala Khan

Abstract read
In one paragraph

Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Black Oat (Current pharmaceutical design · 2026
    Article
  2. Review
  3. Article
  4. Phyto-pharmacological wonders of genusSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
  5. Unlocking the medicinal arsenal ofHealth science reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohammad Abdullah TaherBangladesh Reference Institute for Chemical Measurements (BRiCM), Laboratory Road Dhaka Bangladesh.ORCID 0000-0002-0701-470X
Ripa KunduDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy University of Dhaka Bangladesh.
Aysha Akter LaboniBangladesh Reference Institute for Chemical Measurements (BRiCM), Laboratory Road Dhaka Bangladesh.
Suriya Akter ShompaDepartment of Pharmacy State University of Bangladesh Dhaka Bangladesh.
Md MoniruzzamanBangladesh Reference Institute for Chemical Measurements (BRiCM), Laboratory Road Dhaka Bangladesh.
Mohammad Mahmudul HasanDepartment of Chemistry University of Dhaka Bangladesh.
Hasin HasnatDepartment of Pharmacy State University of Bangladesh Dhaka Bangladesh.
Md Mehedi HasanBangladesh Reference Institute for Chemical Measurements (BRiCM), Laboratory Road Dhaka Bangladesh.
Mala KhanBangladesh Reference Institute for Chemical Measurements (BRiCM), Laboratory Road Dhaka Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: This study investigated the biochemical components present in the leaves of Methodology: Fourier Transform Infrared (FT-IR) spectroscopy, Gas Chromatography-Mass Spectrometry (GC-MS), and Mass Spectral analysis were employed to identify and characterize the compounds in Results and discussion: FT-IR spectroscopic analysis revealed significant molecular vibrations at frequencies of 3265.63, 2853.81, 1638.60, 1469.21, and 1384.95 cm⁻¹, indicating the presence of specific functional groups. The GC-MS analysis identified distinct compounds, such as "aR-Turmerone," "Curlone," "7,8-Epoxylanostan-11-ol, 3-acetoxy-," "13-Docosenamide, (Z)-," "Phenol, 3,5-bis(1,1-dimethylethyl)-," "9,19-Cyclolanostan-3-ol, 24,24-epoxymethano-, acetate," and "Quinoline-5,8-dione-6-ol, 7-[[(4-cyclohexylbutyl)amino]methyl]-." These compounds exhibited potential therapeutic applications. Their cytotoxic, antimicrobial, antidiarrheal, anti-hyperglycemic, and pain-relieving properties were evaluated by comparing them with reference ligands targeting specific receptors, including dihydrofolate reductase (DHFR), epidermal growth factor receptor (EGFR), kappa opioid receptor (KOR), glucose transporter 3 (GLUT 3), and cyclooxygenase 2 (COX-2). Conclusion: The results of this study suggest that Cissus assamica leaves contain bioactive compounds with potential therapeutic benefits for treating infections, diarrhea, hyperglycemia, and pain. However, further research is needed to conduct comprehensive phytochemical screening and establish the precise mechanisms of action for the crude extract or the plant-derived compounds.

Indexed as

FT‐IRGC–MS/MSmolecular dockingreceptor

Identifiers

PMID39328981
PMCPMC11424361

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.