Evidence map›Paper›PMID 39328856›Full record

ArticleWorld journal of clinical cases2024

Prognostic factors of early recurrence after complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Chao-Yu Chen, Tzu-Hao Huang, Li-Wen Lee, Jrhau Lung, Yu-Che Ou, Chien-Hui Hung, Huei-Chieh Chuang, Min-Chi Chen, Ting-Yao Wang

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Article in World journal of clinical cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chao-Yu ChenDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Tzu-Hao HuangDivision of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Li-Wen LeeDepartment of Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Jrhau LungCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Yu-Che OuDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Chien-Hui HungGraduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.
Huei-Chieh ChuangDepartment of Anatomic Pathology, Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Min-Chi ChenDepartment of Public Health, Chang Gung University, Taoyuan 333, Taiwan.
Ting-Yao WangDepartment of Early Childhood Care and Education, Shu-Zen Junior College of Medicine and Management, Kaohsiung 821, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) offer the potential for long-term survival in peritoneal carcinomatosis, outcomes following CRS/HIPEC vary significantly.

aimTo identify the clinical factors associated with progression-free survival (PFS) after complete CRS/HIPEC in patients with colorectal/high-grade appendiceal, ovarian, and gastric cancers.

methodsWe retrospectively evaluated the risk of recurrence within 1 year after CRS/HIPEC and its impact on overall survival (OS) in patients recruited between 2015 and 2020. Logistic regression models were used to assess the prognostic factors for the risk of recurrence within 1 year. Kaplan-Meier survival curves and Cox proportional hazards models were used to evaluate the association between recurrence and OS.

resultsOf the 80 enrolled patients, 39 had an unfavorable PFS (< 1 year) and 41 had a favorable PFS (≥ 1 year). Simple logistic models revealed that the patients with a completeness of cytoreduction score of 0 (CC-0) or length of CRS ≤ 6 h had a favorable PFS [odds ratio (OR) = 0.141,

conclusionAchieving CC-0 was associated with a lower early recurrence rate and improved long-term survival. This study underscores the importance of selecting appropriate candidates for CRS/HIPEC to manage peritoneal carcinomatosis.

Indexed as

Cytoreductive surgeryHyperthermic intraperitoneal chemotherapyPeritoneal metastasisPredictorRecurrence

Identifiers

PMID39328856
PMCPMC11326106

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.