Evidence map›Paper›PMID 39328361›Full record

ArticleResearch in autism spectrum disorders2024

The Effects of the COVID-19 Pandemic on Mental Health in Mothers of Autistic Children and Mothers of Children with Fragile X Syndrome.

Carly Moser, Laura Friedman, Katherine Bangert, Alexandra Hickey, Jennifer Sun, Jessica Klusek

Abstract read
In one paragraph

Article in Research in autism spectrum disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20-75 Years of Age.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carly MoserDepartment of Communication Sciences and Disorders, University of South Carolina, 1705 College Street, Columbia SC 29208, USA.
Laura FriedmanDepartment of Communication Sciences and Disorders, University of South Carolina, 1705 College Street, Columbia SC 29208, USA.
Katherine BangertDepartment of Communication Sciences and Disorders, University of South Carolina, 1705 College Street, Columbia SC 29208, USA.
Alexandra HickeyDepartment of Communication Sciences and Disorders, University of South Carolina, 1705 College Street, Columbia SC 29208, USA.
Jennifer SunDepartment of Communication Sciences and Disorders, University of South Carolina, 1705 College Street, Columbia SC 29208, USA.
Jessica KlusekDepartment of Communication Sciences and Disorders, University of South Carolina, 1705 College Street, Columbia SC 29208, USA.

Funding

Aging Symptom Trajectories in Mother Carriers of the FMR1 PremutationR01AG073374 · NIA · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI Jessica Klusek · 2022 to 2026
$3.4M
Defining the Language Phenotype of the FMR1 PremutationR21DC017804 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KLUSEK, JESSICA · 2019 to 2021
$684k
NIA NIH HHS R01 AG073374NIDCD NIH HHS R21 DC017804
6 · The paper itself

Abstract

Background: The COVID-19 pandemic adversely affected the mental health of American mothers and mothers of children with disabilities may have been disproportionately impacted. The present study characterized psychological well-being, social support, and caregiving responsibilities during the pandemic across mothers of children with autism, fragile X syndrome (FXS), and neurotypical children. Methods: Participants were 54 mothers of children with FXS, 46 mothers of autistic children, and a control group of 80 mothers of neurotypical children. Mothers completed questionnaires on depressive and anxiety symptoms, perceived decline in psychological well-being due to the pandemic, pandemic-related changes in caregiving responsibilities, and levels of social support. Results: Over half of the mothers of children with autism and over one-third of the mothers of children with FXS reported clinically significant symptoms of depression and anxiety, with rates significantly higher than the control mothers. Though all mothers reported a surge in caregiving responsibilities, mothers of children with FXS experienced greater increases in caregiving responsibilities and social support was lower in both disability groups. Caregiving responsibilities and social support were associated with psychological well-being due to the pandemic across all groups. Conclusions: Findings highlight the harsh impact of the pandemic on the mental health of mothers of children with FXS and autism. The staggering rate of clinical depressive and anxiety symptoms reported by these groups underscores the urgent need for improved access to psychological services and family-centered supports, with increased caregiving responsibilities and inadequate social support representing important risk factors for mental health problems.

Indexed as

anxietycaregiver burdendepressionFMR1Psychological well-beingsocial support

Identifiers

PMID39328361
PMCPMC11423899

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.