Evidence map›Paper›PMID 39328146›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2024

Impact of air pollution exposure on the severity of major depressive disorder: Results from the DeprAir study.

E Borroni, M Buoli, G Nosari, A Ceresa, L Fedrizzi, L M Antonangeli, P Monti, V Bollati, A C Pesatori, M Carugno

Abstract read
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. European Psychiatry: 2024 in review.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

E BorroniEPIGET Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.ORCID 0000-0001-9303-2578
M BuoliDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
G NosariDepartment of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0002-1591-2139
A CeresaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.ORCID 0000-0001-6850-0958
L FedrizziOccupational Health Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
L M AntonangeliEPIGET Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.ORCID 0000-0002-2693-1546
P MontiEPIGET Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.ORCID 0000-0001-8185-497X
V BollatiEPIGET Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.ORCID 0000-0002-0370-9598
A C PesatoriEPIGET Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.ORCID 0000-0002-0261-3252
M CarugnoEPIGET Lab, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.ORCID 0000-0001-5212-2489

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMajor depressive disorder (MDD) is one of the most prevalent medical conditions worldwide. Different factors were found to play a role in its etiology, including environmental ones (e.g., air pollution). The aim of this study was to evaluate the association between air pollution exposure and MDD severity.

methodsFour hundred sixteen MDD subjects were recruited. Severity of MDD and functioning were evaluated through five rating scales: Montgomery-Asberg Depression Rating Scale (MADRS), Hamilton Depression Rating Scale (HAMD), Clinical Global Impression (CGI), Global Assessment of Functioning (GAF), and Sheehan Disability Scale (SDS). Daily mean estimates of particulate matter with diameter ≤10 (PM10) and 2.5 μm (PM2.5), nitrogen dioxide (NO

resultsTwo-thirds of subjects were women and one-third had a family history of depression. Most women had depression with symptoms of anxiety, while men had predominantly melancholic depression. NO

conclusionsExposure to air pollution worsens MDD severity, with hypersusceptibility and lower temperatures being exacerbating factors.

Indexed as

Air PollutionMajor Depressive DisorderParticulate MatterSeverity of Illness IndexAdultAir PollutantsEnvironmental ExposureFemaleHumansMaleMiddle AgedNitrogen DioxidePsychiatric Status Rating ScalesAir PollutantsNitrogen DioxideParticulate Matterair pollutiondepression severityenvironmental healthmajor depressive disorder

Identifiers

PMID39328146
PMCPMC11457114

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.