Evidence map›Paper›PMID 39328137›Full record

ArticleCurrent pharmaceutical biotechnology2025

Anti-Mullerian Hormone Induces

Hoda M Abouzeid, Ingy M Hashad, Mona Rady, Sahar M Abdel-Maksoud

Abstract read
PubMed Publisher
In one paragraph

Article in Current pharmaceutical biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hoda M AbouzeidBiochemistry Department, Faculty of Pharmacy & Biotechnology, German University in Cairo, Cairo, Egypt.
Ingy M HashadBiochemistry Department, Faculty of Pharmacy & Biotechnology, German University in Cairo, Cairo, Egypt.ORCID 0000-0001-8265-7353
Mona RadyMicrobiology, Immunology and Biotechnology Department, Faculty of Pharmacy & Biotechnology, German University in Cairo, Cairo, Egypt.ORCID 0000-0002-7561-853X
Sahar M Abdel-MaksoudBiochemistry Department, Faculty of Pharmacy & Biotechnology, German University in Cairo, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnti-Mullerian hormone (AMH) plays a pivotal role in follicular growth and atresia. Recent studies highlighted the role of AMH in attenuating granulosa cell apoptosis and subsequent follicular atresia. Despite the raising understanding of the role of AMH in folliculogenesis, and its contribution to the pathophysiology of certain diseases such as polycystic ovary syndrome, the effect of AMH on the expression of genes regulating folliculogenesis is stills limited.

objectiveThis study aims to gain insights into the effect of AMH on atresia regulating genes.

method

resultsIn this study, AMH significantly enhanced the expression of Foxo1 and Sirt1 gene compared to the control group. On the contrary, AMH did not modulate the expression of p53, Bim, or Bax genes. AMH was also found to increase serum FSH and LH levels in a dosedependent manner.

conclusionThis study demonstrated the capability of AMH to induce

Indexed as

Anti-Mullerian HormoneForkhead Box Protein O1OvarySirtuin 1AnimalsFemaleFollicle Stimulating HormoneGene Expression RegulationLuteinizing HormoneMiceMice, Inbred C57BLAnti-Mullerian HormoneFollicle Stimulating HormoneForkhead Box Protein O1Foxo1 protein, mouseLuteinizing HormoneSirt1 protein, mouseSirtuin 1Anti-Mullerian hormone (AMH)atresiaBax.BimFoxo1p53Polycystic ovary syndrome (PCOS)Sirt1

Identifiers

PMID39328137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.