Evidence map›Paper›PMID 39328051›Full record

ArticleNeurorehabilitation and neural repair2025

Delayed Cortical Responses During Reactive Balance After Stroke Associated With Slower Kinetics and Clinical Balance Dysfunction.

Jacqueline A Palmer, Aiden M Payne, Jasmine L Mirdamadi, Lena H Ting, Michael R Borich

Abstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jacqueline A PalmerDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.ORCID 0000-0003-0021-4589
Aiden M PayneDepartment of Psychology, College of Arts and Sciences, Florida State University, Tallahassee, FL, USA.
Jasmine L MirdamadiDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Lena H TingDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Michael R BorichDivision of Physical Therapy, Department of Rehabilitation Medicine, Emory University, Atlanta, GA, USA.

Funding

MULTICENTER CAREER DEVELOPMENT PROGRAM FOR PHYSICAL AND OCCUPATIONAL THERAPYK12HD055931 · NICHD · WASHINGTON UNIVERSITY · PI HAYES, MARCIE HARRIS · 2007 to 2021
$12.7M
Neuromechanical Modeling of Postural Responses:Mechanisms of Balance Impairments in Parkinson's DiseaseR01HD046922 · NICHD · GEORGIA INSTITUTE OF TECHNOLOGY · PI Michael Robert Borich, Lena H Ting · 2004 to 2026
$7.7M
Udall Parkinson's Disease Research Center at Emory UniversityP50NS098685 · NINDS · EMORY UNIVERSITY · PI SMITH, YOLAND · 2016 to 2020
$6.7M
Individual-specific engagement of cortical resources for standing balance control in aging and post strokeR01AG072756 · NIA · EMORY UNIVERSITY · PI Michael Robert Borich, Lena H Ting · 2022 to 2026
$3.0M
From Cells to Systems and Applications: Computational Neuroscience Training at EmT90DA032466 · NIDA · EMORY UNIVERSITY · PI JAEGER, DIETER, STANLEY, GARRETT B. · 2011 to 2015
$817k
Investigating cerebrovascular regulation during exercise as a factor influencing cortical resource engagement for balance control with agingR00AG075255 · NIA · UNIVERSITY OF MINNESOTA · PI Jacqueline A Palmer · 2024 to 2026
$742k
Investigating cerebrovascular regulation during exercise as a factor influencing cortical resource engagement for balance control with agingK99AG075255 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI PALMER, JACQUELINE A · 2022 to 2023
$234k
Investigating the error-related negativity and the balance N1 in children with anxiety disordersF32MH129076 · NIMH · FLORIDA STATE UNIVERSITY · PI PAYNE, AIDEN MICHAEL · 2022 to 2024
$218k
Cortical connectivity during functional balance reactions in stroke survivorsF32HD096816 · NICHD · EMORY UNIVERSITY · PI PALMER, JACQUELINE A · 2018 to 2021
$162k
Neural correlates of whole-body motion perception during balance perturbations in stroke survivors and their relationship to balance functionF32HD105458 · NICHD · EMORY UNIVERSITY · PI MIRDAMADI, JASMINE · 2021 to 2022
$134k
NIA NIH HHS K99 AG075255NIA NIH HHS R00 AG075255NIA NIH HHS R01 AG072756NICHD NIH HHS F32 HD096816NICHD NIH HHS F32 HD105458NICHD NIH HHS K12 HD055931NICHD NIH HHS R01 HD046922NIDA NIH HHS T90 DA032466NIMH NIH HHS F32 MH129076NINDS NIH HHS P50 NS098685
6 · The paper itself

Abstract

backgroundSlowed balance and mobility after stroke have been well-characterized. Yet the effects of unilateral cortical lesions on whole-body neuromechanical control is poorly understood, despite increased reliance on cortical resources for balance and mobility with aging.

methodsUsing electroencephalography, we assessed cortical N1 responses evoked over fronto-midline regions (Cz) during backward support-surface perturbations loading both legs and posterior-lateral directions that preferentially load the paretic or nonparetic leg in individuals' post-stroke and age-matched controls. We tested relationships between cortical responses and clinical balance/mobility function, as well as to center of pressure (CoP) rate of rise (RoR) during balance recovery.

resultsCortical N1 responses were smaller and delayed after stroke (

conclusionsIndividuals after stroke may be limited in their balance ability by the slowed speed of their cortical responses to destabilization. In particular, paretic leg loading may reveal cortical response impairments that reflect reduced paretic motor capacity.

Indexed as

Cerebral CortexElectroencephalographyPostural BalanceStrokeAgedEvoked PotentialsFemaleHumansMaleMiddle AgedSensation Disorderselectroencephalographyerror-related negativityfallskineticsmobilityreactive balance

Identifiers

PMID39328051
PMCPMC11723813

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.