Evidence map›Paper›PMID 39327323›Full record

ArticleInternational ophthalmology2024

Vascular changes in the retinal capillary network in fellow eye of the patients with central retinal artery occlusion.

Seyed Ali Tabatabaei, Zohre Ebrahimi, Mohammad Soleimani, Zahra Mahdizad, Mehrnaz Atighechian, Fatemeh Bazvand, Mohammadreza Mehrabi Bahar, Arash Mirzaei, Shakiba Dehghani

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Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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9 authors.

Seyed Ali TabatabaeiFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Zohre EbrahimiFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad SoleimaniFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Zahra MahdizadFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mehrnaz AtighechianFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Fatemeh BazvandFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Mohammadreza Mehrabi BaharFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran. Mreza.mehrabibahar@gmail.com.ORCID http://orcid.org/0000-0001-8829-053X
Arash MirzaeiFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Shakiba DehghaniFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to evaluate the retinal vascular changes in the superficial and deep retinal vascular networks in the fellow eye of patients with central retinal artery occlusion (CRAO) and compare them with controls using optical coherence tomography angiography (OCT-A).

methodsIn a cross-sectional study, 27 patients with CRAO and 189 normal controls were included. Ophthalmic examination and OCT-A images were performed on all participants.

resultsThe total vascular density of the superficial capillary network in the 6-mm scan was significantly lower in the fellow eye of patients with CRAO than in the control group (p = 0.02). No significant difference was observed in the FAZ area of the affected eyes and their fellow eyes compared with the controls. Total vascular density at 300 microns around the fovea was lower in the fellow eye compared with the control group (p = 0.034).

conclusionsThe retinal vascular network changes in the fellow eyes of patients with CRAO suggest that persistent microvascular changes may be present before the onset of CRAO. This finding indicates that such changes could serve as an early diagnostic window for systemic vascular changes before catastrophic vascular events occur.

Indexed as

CapillariesFluorescein AngiographyFundus OculiRetinal Artery OcclusionRetinal VesselsTomography, Optical CoherenceAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedVisual AcuityCentral retinal artery occlusionFoveal avascular zoneMicrocirculationOptical coherence tomography angiographyRetinal ischemiaStroke

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.