Trial reportSurgical endoscopy2024
Efficacy of colonoscopic re-examination across the entire colon: a randomized controlled trial.
Trial report in Surgical endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03268200 (The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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The Effect of Segmental Re-examination of Colon for Adenoma Detection in Colonoscopy: a Randomized, Controlled Trial
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn standard colonoscopic examinations, some polyps may be missed during the withdrawal phase. Re-examination of the right colon can improve the adenoma detection rate (ADR). However, the effectiveness of applying this re-examination strategy to the entire colon remains unknown. We investigated whether re-examination could increase the detection rate of polyps and adenomas throughout the colon.
methodsA randomized, controlled, single-center trial (NCT03268200) was conducted in a university hospital. Patients aged 45-75 years were randomly assigned to either the study or control group. For patients in the control group, observation and polypectomy were performed once using the standard colonoscopy method. For patients in the study group, polypectomy was repeated twice during the withdrawal phase after the initial insertion of the colonoscope. These examinations were performed in the right transverse and left colons. The primary endpoints were the polyp detection rate (PDR) and ADR, defined as the proportion of patients with ≥ 1 polyp and ≥ 1 adenoma, respectively.
resultsOverall, 406 patients were enrolled (study group, n = 210; control group, n = 196) and analyzed. Generally, PDRs and ADRs were similar between the study (withdrawal 1 + 2) and control groups (withdrawal 1), except for the right colon. However, the second withdrawal review increased number of polyps and adenomas in the overall, right, mid, and left colon, respectively.
conclusionThe results of this trial indicated that re-examination of the entire colon during colonoscopy could be beneficial for detecting concealed polyps in patients at risk of interval cancer.
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