Evidence map›Paper›PMID 39327017›Full record

Observational studyJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

Intrapatient Intermetastatic Heterogeneity Determined by Triple-Tracer PET Imaging in mCRPC Patients and Correlation to Survival: The 3TMPO Cohort Study.

Frédéric Pouliot, Fred Saad, Etienne Rousseau, Patrick O Richard, Atefeh Zamanian, Stephan Probst, Éric Lévesque, Vincent Castonguay, Nicolas Marcoux, Michele Lodde and 13 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Comparison of mCRPC [European journal of nuclear medicine and molecular imaging · 2026
    Article
  8. Effect of bone marrow disease on hematologic toxicity and response to [European journal of nuclear medicine and molecular imaging · 2026
    Article
  9. Article
  10. Review
  11. Development and In Vitro Evaluation of [International journal of molecular sciences · 2025
    Article
  12. Review
  13. Review
  14. Preclinical Theranostic Profiling of [Molecules (Basel, Switzerland) · 2025
    Article
  15. Review
  16. The tumour sink effect onCancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Observational
  17. The role of PSMA-based radioligand therapy in hormone-sensitive prostate cancer.European journal of nuclear medicine and molecular imaging · 2025
    Review
  18. Review
  19. Review
  20. Dual targeting PET tracer [Theranostics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Frédéric PouliotOncology Axis, CHU de Québec-Université Laval Research Center, Quebec City, Quebec, Canada; frederic.pouliot@crchudequebec.ulaval.ca brigitte.guerin2@usherbrooke.ca.
Fred SaadDivision of Urology, Department of Surgery, Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montréal, Quebec, Canada.
Etienne RousseauDepartment of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Patrick O RichardDivision of Urology, Department of Surgery, Centre Hospitalier Universitaire de Sherbrooke and Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.
Atefeh ZamanianOncology Axis, CHU de Québec-Université Laval Research Center, Quebec City, Quebec, Canada.
Stephan ProbstDivision of Nuclear Medicine, Faculty of Medicine, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montréal, Quebec, Canada.
Éric LévesqueDivision of Hemato-Oncology, Department of Medicine, CHU de Québec-Université Laval, Quebec City, Quebec, Canada.
Vincent CastonguayDivision of Hemato-Oncology, Department of Medicine, CHU de Québec-Université Laval, Quebec City, Quebec, Canada.
Nicolas MarcouxDivision of Hemato-Oncology, Department of Medicine, CHU de Québec-Université Laval, Quebec City, Quebec, Canada.
Michele LoddeSurgery Urology Department, CHU de Québec-Université Laval, Quebec City, Quebec, Canada.
Daniel JuneauNuclear Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Zineb HamilouHemato-Oncology, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Jean-Baptiste LattoufDivision of Urology, Department of Surgery, Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montréal, Quebec, Canada.
François-Alexandre ButeauDepartment of Radiology and Nuclear Medicine, and Cancer Research Centre, Université Laval, Quebec City, Quebec, Canada.
Michel PavicMedical Oncology, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada; and.
Jean-François CastillouxMedical Oncology, Centre Intégré Universitaire de Santé et Services Sociaux de l'Estrie-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada; and.
Bertrand NeveuOncology Axis, CHU de Québec-Université Laval Research Center, Quebec City, Quebec, Canada.
Guillaume F BouvetOncology Axis, CHU de Québec-Université Laval Research Center, Quebec City, Quebec, Canada.
Catherine AllardUnité de Recherche Clinique et Épidémiologique, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.
Amélie TétuUnité de Recherche Clinique et Épidémiologique, Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.
Brigitte GuérinDepartment of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; frederic.pouliot@crchudequebec.ulaval.ca brigitte.guerin2@usherbrooke.ca.
Jean-Mathieu BeauregardOncology Axis, CHU de Québec-Université Laval Research Center, Quebec City, Quebec, Canada.
3TMPO Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrapatient intermetastatic heterogeneity (IIH) has been demonstrated in metastatic castration-resistant prostate cancer (mCRPC) patients and is of the utmost importance for radiopharmaceutical therapy (RPT) eligibility. This study was designed to determine the prevalence of IIH and RPT eligibility in mCRPC patients through a triple-tracer PET imaging strategy.

Indexed as

Fluorodeoxyglucose F18Neoplasm MetastasisProstatic Neoplasms, Castration-ResistantAgedAged, 80 and overCohort StudiesGallium IsotopesGallium RadioisotopesHumansMaleMiddle AgedOligopeptidesOrganometallic CompoundsPositron Emission Tomography Computed TomographyProspective StudiesSurvival AnalysisFluorodeoxyglucose F18gallium Ga 68 dotatateGallium IsotopesGallium RadioisotopesOligopeptidesOrganometallic CompoundsIIHintrapatient intermetastatic heterogeneitymetastatic castration-resistant prostate cancermolecular imagingPET

Identifiers

PMID39327017
PMCPMC11533914

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.