Evidence map›Paper›PMID 39325792›Full record

ArticlePloS one2024

Immunological effects of vitamin c and zinc on tilapia (Orechromis niloticus) exposed to cold water stress.

Ahmed Mustafa, Maryam Belavilas, Rumman Hossain, Israt Mishu

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Aquaculture nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ahmed MustafaDepartment of Biological Sciences, Purdue University Fort Wayne, IN, United States of America.ORCID 0000-0002-0193-7685
Maryam BelavilasDepartment of Biological Sciences, Purdue University Fort Wayne, IN, United States of America.
Rumman HossainDepartment of Biological Sciences, Purdue University Fort Wayne, IN, United States of America.ORCID 0000-0002-1016-0265
Israt MishuDepartment of Biological Sciences, Purdue University Fort Wayne, IN, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the immunological and growth effects of Vitamin C and Zinc supplementation on Nile tilapia (Oreochromis niloticus) subjected to cold water stress. Nile tilapia fingerlings were housed in eight 20-gallon tanks at Purdue University, acclimated to 26 ± 2°C water conditions before the experiment. The tilapia was divided into groups with varying water temperatures and feed supplements: control fish in warm water, and experimental groups in cold water with increased levels of Vitamin C and Zinc. Stress was induced by lowering the water temperature to 15 ± 2°C in four tanks, while the remaining tanks were kept at the optimal growth temperature. Results demonstrated that Vitamin C and Zinc supplementation significantly enhanced immune response and muscle regeneration in cold-stressed tilapia, allowing them to achieve growth rates comparable to those of control fish in optimal warm water conditions. These findings highlight the potential benefits of combined Vitamin C and Zinc supplementation in improving the immune response and growth performance of tilapia under suboptimal temperature conditions.

Indexed as

Ascorbic AcidCichlidsDietary SupplementsZincAnimalsCold TemperatureStress, PhysiologicalTilapiaWaterAscorbic AcidWaterZinc

Identifiers

PMID39325792
PMCPMC11426438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.