Evidence map›Paper›PMID 39325574›Full record

ArticleJournal of orthopaedic trauma2024

Bicortical Compression and Construct Stability With Variable Pitch Locking Screws in Cadaveric Specimens.

Zachary A Koroneos, Shelby Alwine, Peter Tortora, Michaela Pitcher, Christian Benedict, Hwabok Wee, Allen Kunselman, Michael Aynardi, Gregory S Lewis

Erratum issuedAbstract read
In one paragraph

Article in Journal of orthopaedic trauma, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Zachary A KoroneosDepartment for Orthopaedics and Rehabilitation, Penn State College of Medicine, Hershey, PA.ORCID 0000-0002-7645-8179
Shelby AlwineDepartment for Orthopaedics and Rehabilitation, Penn State College of Medicine, Hershey, PA.ORCID 0009-0009-8234-1506
Peter TortoraPenn State College of Medicine, Hershey, PA; and.ORCID 0009-0006-7626-9446
Michaela PitcherPenn State College of Medicine, Hershey, PA; and.
Christian BenedictPenn State College of Medicine, Hershey, PA; and.
Hwabok WeeDepartment of Mechanical Engineering, The Pennsylvania State University, University Park, PA.
Allen KunselmanDivision of Biostatistics and Bioinformatics, Department of Public Health Sciences, The Pennsylvania State University, Hershey, PA.ORCID 0000-0001-8485-2953
Michael AynardiDepartment for Orthopaedics and Rehabilitation, Penn State College of Medicine, Hershey, PA.ORCID 0000-0002-7648-3868
Gregory S LewisDepartment for Orthopaedics and Rehabilitation, Penn State College of Medicine, Hershey, PA.ORCID 0000-0002-3673-0182

Funding

Fracture Fixation Biomechanics Simulator with Adaptive Virtual CoachingR01EB029207 · NIBIB · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LEWIS, GREGORY STEPHEN, REID , JOHN SPENCE · 2020 to 2023
$1.2M
Arthrex, National Institute of Biomedical Imaging and Bioengineering R01EB029207NIBIB NIH HHS R01 EB029207
6 · The paper itself

Abstract

objectivesA variable pitch locking screw is intended to provide interfragmentary compression combined with fixed angle stability of locking plate constructs. The objective of this study was to compare variable pitch locking screws (3.5-mm KreuLock Ti locking compression screws, Arthrex Inc., Naples, FL) with standard locking screws (from the same manufacturer) in bicortical fixation scenarios in cadaver bone by assessing (1) interfragmentary compression and plate-bone compression and (2) construct biomechanical stability.

methodsNine matched pairs of fresh-frozen cadaveric specimens with an average age of 67.2 years (range, 37-83) were used. Interfragmentary compression and plate-bone compression associated with insertion of single bicortical screws were compared between the variable pitch and standard locking screws at increasing levels of torque. The specimens tested were distal tibiae having a simulated longitudinal fracture. Additionally, fibulae were osteotomized to create a stable longitudinal fracture pattern and were fixed with a 5-screw plate construct with either all variable pitch or all standard locking screws. One of the 5 screws was placed across the osteotomy without lagging. Fibulae were tested cyclically with axial with torsional loading to compare displacements, rotation, and loads at failure or tested in 4-point bending to compare construct stiffness and maximum force to failure.

resultsInterfragmentary and plate-bone compression forces in the distal tibia model varied across specimens but were significantly higher with variable pitch locking screws compared with standard locking screws [512 N (SD = 324 N) vs. 79 N (SD = 64 N), P = 0.002, and 242 N (SD = 119 N) vs. 104 N (SD = 123 N), P = 0.028, respectively]. In cyclic loading of fibula constructs, no significant differences were detected in construct axial displacement or angular displacement (P > 0.05). In 4-point bending, no differences were detected in maximum force or bending stiffness (P > 0.05).

conclusionsVariable pitch locking screws produced interfragmentary compression between cortices and plate-bone compression that was greater than that produced by standard locking screws. In a stable bicortical fibula fixation scenario under external loading, the stability of variable pitch locking screw constructs was similar to constructs with standard locking screws.

Indexed as

Bone PlatesBone ScrewsCadaverFracture Fixation, InternalAdultAgedAged, 80 and overBiomechanical PhenomenaCompressive StrengthEquipment Failure AnalysisFemaleHumansMaleMiddle AgedTibial Fractures

Identifiers

PMID39325574
PMCPMC13370673

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.