Evidence map›Paper›PMID 39325326›Full record

SynthesisHernia : the journal of hernias and abdominal wall surgery2024

Risk factors for incisional hernia after open abdominal aortic aneurysm repair: a systematic review and meta-analysis.

Nandita N Mahajan, Carlos Andre Balthazar da Silveira, Julia Adriana Kasmirski, Diego Laurentino Lima, Gabriele Eckerdt Lech, Luiza Bertolli Lucchese Moraes, Carolina Moronte Sturmer, Leandro Totti Cavazzola, Prashanth Sreeramoju

Abstract readMeta-AnalysisSystematic Review
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In one paragraph

Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Variable use of modern abdominal wall closure techniques at emergency laparotomy - an international, cross-sectional survey of surgical practice.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nandita N MahajanDepartment of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY, 10467, USA.
Carlos Andre Balthazar da SilveiraBahiana School of Medicine and Public Health, Salvador, Bahia, Brazil.
Julia Adriana KasmirskiUniversity of São Paulo, São Paulo, Brazil.
Diego Laurentino LimaDepartment of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY, 10467, USA. dilaurentino@gmail.com.ORCID 0000-0001-7383-1284
Gabriele Eckerdt LechPontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Luiza Bertolli Lucchese MoraesPontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Carolina Moronte SturmerPontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Leandro Totti CavazzolaFederal University of Rio Grande do Sul, Porto Alegre, Brazil.
Prashanth SreeramojuDepartment of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY, 10467, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of incisional hernia (IH) after an open abdominal aortic aneurysm (AAA) repair can reach up to 35%, contributing to long-term morbidity. Individual studies have been limited in identifying modifiable risk factors for IH after an open AAA repair. This meta-analysis aims to review all the risk factors for IH after an open AAA repair.

methodsWe searched Cochrane Central, Embase, PubMed, MEDLINE, and Web of Science databases for original studies. Risk factors assessed were age, sex, comorbidities, surgical incision, blood loss, and surgical site infection (SSI). Data analysis was done using RStudio 4.1.2. We computed Relative Risk (RR) for dichotomous outcomes and Mean differences (MD) with 95% Confidence Interval (CI) for continuous outcomes. P-values less than 0.05 were considered statistically significant.

resultsTen studies met the inclusion criteria among 1,795 screened articles. Among those ten studies, there were a total of 1,806 patients of which 341 patients developed IH. Older age (Mean 69.6-70.7 years, MD 1.39 years, CI [1.12-1.66], P < 0.01), midline vertical incision (RR 1.55, CI [1.06-2.25], P = 0.02) and increased intraoperative blood loss (MD 429.8 ml, CI [234.8- 624.8], P < 0.01) were associated with an increased incidence of IH. Surgical site infection (SSI) was noted as a risk factor for IH after open AAA repair (RR 2.36, CI [1.31-4.24], P = 0.004). No statistically significant association was found between the incidence of IH and sex (RR 1.0, CI [0.8-1.14], P = 0.98), smoking (RR 1.01, CI [0.93-1.09], P = 0.88), diabetes (RR 1.38, CI [0.85-2.25], P = 0.19), and chronic kidney disease (RR 1.55, CI [0.47-5.09], P = 0.46).

conclusionThis meta-analysis shows that age, midline vertical incision, intraoperative blood loss, and SSI are risk factors for IH after open AAA repair.

Indexed as

Aortic Aneurysm, AbdominalIncisional HerniaSurgical Wound InfectionAge FactorsHumansRisk FactorsAortic aneurysmIncisional herniaOpen aortic aneurysm repairSurgical site infection

Identifiers

PMID39325326

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.