ArticleActa neurologica Belgica2024
Incidence of contrast-induced neurotoxicity following endovascular treatment of unruptured intracranial aneurysms: a single-centre cohort study.
Article in Acta neurologica Belgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Late-Onset Contrast-Induced Encephalopathy After Stent-Assisted Coiling: A Case Report and Review of the Literature.Brain sciences · 2026Article
- Contrast-Induced Neurotoxicity: A Rare and Poorly Understood Entity.Annals of Indian Academy of Neurology · 2026Article
- The Australian Diagnostic Criteria for Contrast-Induced Encephalopathy.Neuroradiology · 2025Article
- Early Detection of Contrast-Induced Encephalopathy Using Somatosensory Evoked Potential Monitoring during Coil Embolization of an Intracranial Aneurysm.Journal of neuroendovascular therapy · 2025Article
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8 authors.
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Abstract
backgroundContrast-induced neurotoxicity (CIN) is a recognised complication of endovascular procedures and has been increasingly observed in recent years. Amongst other clinical gaps, the precise incidence of CIN is unclear, particularly following intracranial interventional procedures.
methodsA retrospective study of consecutive patients undergoing elective endovascular treatment of unruptured intracranial aneurysms (UIAs) was performed. Patients with previously ruptured aneurysms were excluded. The primary aim of this study was to determine the incidence of CIN following endovascular UIA treatment. Our secondary aim was to isolate potential predictive factors for developing CIN.
resultsFrom 2017 to 2023, a total of 158 patients underwent endovascular UIA treatment, with a median age of 64 years (IQR: 54-72), and 70.3% of female sex. Over the study period, the crude incidence of CIN was 2.5% (95% CI: 0.7 - 6.4%). The most common clinical manifestation of CIN was confusion (75%) and seizures (50%). Statistical analysis was conducted, and prolonged procedural duration was found be significantly associated with developing CIN (OR 12.55; p = 0.030).
conclusionClinicians should be aware of the risk of CIN following endovascular neurointervention, particularly following technically challenging cases resulting in prolonged procedural time.
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