Evidence map›Paper›PMID 39325075›Full record

ArticleInternational ophthalmology2024

Retrocorneal membrane interception enhanced penetrating canaloplasty for patients with open angle glaucoma secondary to ICE syndrome.

Mengtian Zhou, Shuqing Zhu, Haoyu Li, Wenqing Ye, Shuxia Xu, Haishuang Lin, Jinxin Li, Jinyuan Chen, Shaodan Zhang, Clement C Tham and 2 more

Abstract read
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In one paragraph

Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Iridocorneal endothelial syndrome.Frontiers in ophthalmology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mengtian Zhou *The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.ORCID http://orcid.org/0000-0002-9621-8076
Shuqing Zhu *The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.ORCID http://orcid.org/0000-0001-6678-4547
Haoyu LiThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.ORCID http://orcid.org/0000-0002-9826-181X
Wenqing YeThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Shuxia XuThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Haishuang LinThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.ORCID http://orcid.org/0000-0002-5750-917X
Jinxin LiThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Jinyuan ChenDepartment of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.ORCID http://orcid.org/0000-0003-1547-5511
Shaodan ZhangThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.
Clement C ThamDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.ORCID http://orcid.org/0000-0003-4407-6907
Ningli WangBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Institute of Ophthalmology, Capital Medical University, No. 1 Dongjiaominxiang Street, Beijing, 100730, Dongcheng District, China. wningli@vip.163.com.
Yuanbo LiangThe Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China. yuanboliang@126.com.ORCID http://orcid.org/0000-0001-9685-7356

Funding

the Foundation for Scientific Research and Development of Wenzhou Medical University QTJ13009the Key Research and Development Projects of Zhejiang Province 2022C03112the National Key Research and Development Project of China 2020YFC2008200the Program for Zhejiang Leading Talent of S&T Innovation 2021R52012the Zhejiang Provincial Program for the Cultivation of Leading Talents in Colleges and Universities 2020099
6 · The paper itself

Abstract

introductionTo assess the efficacy and safety of retrocorneal membrane interception (RMI)-enhanced penetrating canaloplasty in glaucoma secondary to iridocorneal endothelial syndrome (GS-ICE) with open angle or small peripheral anterior synechiae (PAS).

methodsA series of 13 patients (13 eyes) with GS-ICE and uncontrolled intraocular pressure (IOP) underwent RMI-enhanced penetrating canaloplasty from March 2019 to October 2020. The patients were followed up at one week, 1 month, 3 months, 6 months, and 12 months, postoperatively. The main outcome measure was surgical success, which was defined as an IOP ≤ 18 mmHg or ≤ 21 mmHg, with glaucoma medications (qualified success), or without glaucoma medications (complete success). Secondary outcome measures were IOP, medication usage, and surgical complications.

resultsAmong the 13 GS-ICE eyes, 12 (92%) achieved qualified success and 10 (77%) achieved complete success at 12 months postoperatively. The mean IOP decreased from 36.41 ± 8.92 mmHg on 3.0 (IQR 0.5) medications before surgery to 17.09 ± 7.71 mmHg (p = 0.0004) on 0.0 (IQR 0.5) medications (p = 0.0004) at 12 months after surgery. Transient hypotony (38%) and hyphema (38%) were the most common complications.

conclusionsRMI-enhanced penetrating canaloplasty appears effective and safe in treating GS-ICE with open angle or small PAS up to one year of follow up.

Indexed as

Glaucoma, Open-AngleIntraocular PressureIridocorneal Endothelial SyndromeAdultAgedFemaleFiltering SurgeryFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeVisual AcuityBleb-independent filtering surgeryGlaucomaIntraocular pressureIridocorneal endothelial syndromePenetrating canaloplastyRetrocorneal membrane interception

Identifiers

PMID39325075

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.